Neuroplasticity Underlying the Comorbidity of Pain and Depression
Joint Authors
Doan, Lisa
Manders, Toby
Wang, Jing
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-25
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Acute pain induces depressed mood, and chronic pain is known to cause depression.
Depression, meanwhile, can also adversely affect pain behaviors ranging from symptomology to treatment response.
Pain and depression independently induce long-term plasticity in the central nervous system (CNS).
Comorbid conditions, however, have distinct patterns of neural activation.
We performed a review of the changes in neural circuitry and molecular signaling pathways that may underlie this complex relationship between pain and depression.
We also discussed some of the current and future therapies that are based on this understanding of the CNS plasticity that occurs with pain and depression.
American Psychological Association (APA)
Doan, Lisa& Manders, Toby& Wang, Jing. 2015. Neuroplasticity Underlying the Comorbidity of Pain and Depression. Neural Plasticity،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1075359
Modern Language Association (MLA)
Doan, Lisa…[et al.]. Neuroplasticity Underlying the Comorbidity of Pain and Depression. Neural Plasticity No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1075359
American Medical Association (AMA)
Doan, Lisa& Manders, Toby& Wang, Jing. Neuroplasticity Underlying the Comorbidity of Pain and Depression. Neural Plasticity. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1075359
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075359