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Modulation of Hippocampal Neural Plasticity by Glucose-Related Signaling
Joint Authors
Mainardi, Marco
Fusco, Salvatore
Grassi, Claudio
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Hormones and peptides involved in glucose homeostasis are emerging as important modulators of neural plasticity.
In this regard, increasing evidence shows that molecules such as insulin, insulin-like growth factor-I, glucagon-like peptide-1, and ghrelin impact on the function of the hippocampus, which is a key area for learning and memory.
Indeed, all these factors affect fundamental hippocampal properties including synaptic plasticity (i.e., synapse potentiation and depression), structural plasticity (i.e., dynamics of dendritic spines), and adult neurogenesis, thus leading to modifications in cognitive performance.
Here, we review the main mechanisms underlying the effects of glucose metabolism on hippocampal physiology.
In particular, we discuss the role of these signals in the modulation of cognitive functions and their potential implications in dysmetabolism-related cognitive decline.
American Psychological Association (APA)
Mainardi, Marco& Fusco, Salvatore& Grassi, Claudio. 2015. Modulation of Hippocampal Neural Plasticity by Glucose-Related Signaling. Neural Plasticity،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1075386
Modern Language Association (MLA)
Mainardi, Marco…[et al.]. Modulation of Hippocampal Neural Plasticity by Glucose-Related Signaling. Neural Plasticity No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1075386
American Medical Association (AMA)
Mainardi, Marco& Fusco, Salvatore& Grassi, Claudio. Modulation of Hippocampal Neural Plasticity by Glucose-Related Signaling. Neural Plasticity. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1075386
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075386