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Glutamatergic Transmission: A Matter of Three
Joint Authors
Martínez-Lozada, Zila
Ortega, Arturo
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-04
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Glutamatergic transmission in the vertebrate brain requires the involvement of glia cells, in a continuous molecular dialogue.
Glial glutamate receptors and transporters are key molecules that sense synaptic activity and by these means modify their physiology in the short and long term.
Posttranslational modifications that regulate protein-protein interactions and modulate transmitter removal are triggered in glial cells by neuronal released glutamate.
Moreover, glutamate signaling cascades in these cells are linked to transcriptional and translational control and are critically involved in the control of the so-called glutamate/glutamine shuttle and by these means in glutamatergic neurotransmission.
In this contribution, we summarize our current understanding of the biochemical consequences of glutamate synaptic activity in their surrounding partners and dissect the molecular mechanisms that allow neurons to take control of glia physiology to ensure proper glutamate-mediated neuronal communication.
American Psychological Association (APA)
Martínez-Lozada, Zila& Ortega, Arturo. 2015. Glutamatergic Transmission: A Matter of Three. Neural Plasticity،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1075408
Modern Language Association (MLA)
Martínez-Lozada, Zila& Ortega, Arturo. Glutamatergic Transmission: A Matter of Three. Neural Plasticity No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1075408
American Medical Association (AMA)
Martínez-Lozada, Zila& Ortega, Arturo. Glutamatergic Transmission: A Matter of Three. Neural Plasticity. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1075408
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075408