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Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence
Joint Authors
Weinstein, Maya
Myers, Vicki
Green, Dido
Schertz, Mitchell
Shiran, Shelly I.
Geva, Ronny
Artzi, Moran
Gordon, Andrew M.
Fattal-Valevski, Aviva
Ben Bashat, Dafna
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-10
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Neuroplasticity studies examining children with hemiparesis (CH) have focused predominantly on unilateral interventions.
CH also have bimanual coordination impairments with bimanual interventions showing benefits.
We explored neuroplasticity following hand-arm bimanual intensive therapy (HABIT) of 60 hours in twelve CH (6 females, mean age 11 ± 3.6 y).
Serial behavioral evaluations and MR imaging including diffusion tensor (DTI) and functional (fMRI) imaging were performed before, immediately after, and at 6-week follow-up.
Manual skills were assessed repeatedly with the Assisting Hand Assessment, Children’s Hand Experience Questionnaire, and Jebsen-Taylor Test of Hand Function.
Beta values, indicating the level of activation, and lateralization index (LI), indicating the pattern of brain activation, were computed from fMRI.
White matter integrity of major fibers was assessed using DTI.
11/12 children showed improvement after intervention in at least one measure, with 8/12 improving on two or more tests.
Changes were retained in 6/8 children at follow-up.
Beta activation in the affected hemisphere increased at follow-up, and LI increased both after intervention and at follow-up.
Correlations between LI and motor function emerged after intervention.
Increased white matter integrity was detected in the corpus callosum and corticospinal tract after intervention in about half of the participants.
Results provide first evidence for neuroplasticity changes following bimanual intervention in CH.
American Psychological Association (APA)
Weinstein, Maya& Myers, Vicki& Green, Dido& Schertz, Mitchell& Shiran, Shelly I.& Geva, Ronny…[et al.]. 2015. Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence. Neural Plasticity،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1075410
Modern Language Association (MLA)
Weinstein, Maya…[et al.]. Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence. Neural Plasticity No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1075410
American Medical Association (AMA)
Weinstein, Maya& Myers, Vicki& Green, Dido& Schertz, Mitchell& Shiran, Shelly I.& Geva, Ronny…[et al.]. Brain Plasticity following Intensive Bimanual Therapy in Children with Hemiparesis: Preliminary Evidence. Neural Plasticity. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1075410
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075410