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Safety and Efficacy of Ferric Carboxymaltose in Anemic Pregnant Women: A Retrospective Case Control Study
Joint Authors
Source
Obstetrics and Gynecology International
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Anemia during pregnancy is commonly caused by iron deficiency and can have severe consequences for both the mother and the developing fetus.
The aim of this retrospective study was to assess the safety and efficacy of intravenous ferric carboxymaltose (FCM) in pregnant women.
Methods.
All women treated with FCM for anemia during pregnancy between 2010 and 2012 at our institution were included.
A matched control group was selected, including women who either were nonanemic or had anemia but were not considered for intravenous iron.
Main outcome measures were maternal safety and pregnancy outcomes.
Results.
The study included 128 patients (FCM: 64; control: 64).
Median FCM dose was 1000 mg and median gestational age at the time of first treatment was 34 weeks and 6 days.
Median Hb increased from 8.4 g/dL (interquartile range 7.7; 8.9 g/dL) at the first FCM administration to 10.7 g/dL (9.8; 11.5 g/dL; n = 46 with available Hb at delivery) at the time of delivery, achieving levels similar to those in the control group (10.8 g/dL [9.8; 11.8 g/dL; n = 48 ]).
No treatment-related adverse events were reported and no statistically significant differences in pregnancy outcomes were observed between groups.
Conclusions.
Within the limitations of this case control study, FCM was a safe and efficient treatment of anemia during pregnancy.
American Psychological Association (APA)
Pels, Anouk& Ganzevoort, Wessel. 2015. Safety and Efficacy of Ferric Carboxymaltose in Anemic Pregnant Women: A Retrospective Case Control Study. Obstetrics and Gynecology International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1075512
Modern Language Association (MLA)
Pels, Anouk& Ganzevoort, Wessel. Safety and Efficacy of Ferric Carboxymaltose in Anemic Pregnant Women: A Retrospective Case Control Study. Obstetrics and Gynecology International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1075512
American Medical Association (AMA)
Pels, Anouk& Ganzevoort, Wessel. Safety and Efficacy of Ferric Carboxymaltose in Anemic Pregnant Women: A Retrospective Case Control Study. Obstetrics and Gynecology International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1075512
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075512