Advances in the Pathogenesis of Cardiorenal Syndrome Type 3
Joint Authors
Clementi, Anna
Ronco, Claudio
Brocca, Alessandra
Virzì, Grazia Maria
Pastori, Silvia
de Cal, Massimo
Clementi, Maurizio
Vescovo, Giorgio
Granata, Antonio
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-04
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Cardiorenal syndrome (CRS) type 3 is a subclassification of the CRS whereby an episode of acute kidney injury (AKI) leads to the development of acute cardiac injury or dysfunction.
In general, there is limited understanding of the pathophysiologic mechanisms involved in CRS type 3.
An episode of AKI may have effects that depend on the severity and duration of AKI and that both directly and indirectly predispose to an acute cardiac event.
Experimental data suggest that cardiac dysfunction may be related to immune system activation, inflammatory mediators release, oxidative stress, and cellular apoptosis which are well documented in the setting of AKI.
Moreover, significant derangements, such as fluid and electrolyte imbalance, metabolic acidosis, and uremia, which are typical features of acute kidney injury, may impair cardiac function.
In this review, we will focus on multiple factors possibly involved in the pathogenesis issues regarding CRS type 3.
American Psychological Association (APA)
Clementi, Anna& Virzì, Grazia Maria& Brocca, Alessandra& de Cal, Massimo& Pastori, Silvia& Clementi, Maurizio…[et al.]. 2015. Advances in the Pathogenesis of Cardiorenal Syndrome Type 3. Oxidative Medicine and Cellular Longevity،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1075533
Modern Language Association (MLA)
Clementi, Anna…[et al.]. Advances in the Pathogenesis of Cardiorenal Syndrome Type 3. Oxidative Medicine and Cellular Longevity No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1075533
American Medical Association (AMA)
Clementi, Anna& Virzì, Grazia Maria& Brocca, Alessandra& de Cal, Massimo& Pastori, Silvia& Clementi, Maurizio…[et al.]. Advances in the Pathogenesis of Cardiorenal Syndrome Type 3. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1075533
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075533