Interaction of H 2S with Calcium Permeable Channels and Transporters
Joint Authors
Xu, Changqing
Yang, Guangdong
Zhang, Weihua
Wu, Lingyun
Wang, Rui
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-11
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
A growing amount of evidence has suggested that hydrogen sulfide (H2S), as a gasotransmitter, is involved in intensive physiological and pathological processes.
More and more research groups have found that H2S mediates diverse cellular biological functions related to regulating intracellular calcium concentration.
These groups have demonstrated the reciprocal interaction between H2S and calcium ion channels and transporters, such as L-type calcium channels (LTCC), T-type calcium channels (TTCC), sodium/calcium exchangers (NCX), transient receptor potential (TRP) channels, β-adrenergic receptors, and N-methyl-D-aspartate receptors (NMDAR) in different cells.
However, the understanding of the molecular targets and mechanisms is incomplete.
Recently, some research groups demonstrated that H2S modulates the activity of calcium ion channels through protein S-sulfhydration and polysulfide reactions.
In this review, we elucidate that H2S controls intracellular calcium homeostasis and the underlying mechanisms.
American Psychological Association (APA)
Zhang, Weihua& Xu, Changqing& Yang, Guangdong& Wu, Lingyun& Wang, Rui. 2015. Interaction of H 2S with Calcium Permeable Channels and Transporters. Oxidative Medicine and Cellular Longevity،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1075590
Modern Language Association (MLA)
Zhang, Weihua…[et al.]. Interaction of H 2S with Calcium Permeable Channels and Transporters. Oxidative Medicine and Cellular Longevity No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1075590
American Medical Association (AMA)
Zhang, Weihua& Xu, Changqing& Yang, Guangdong& Wu, Lingyun& Wang, Rui. Interaction of H 2S with Calcium Permeable Channels and Transporters. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1075590
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075590