Biomarkers of Dietary Polyphenols in Cancer Studies: Current Evidence and Beyond
Joint Authors
Wang, Jia-Sheng
Wang, Jincheng
Tang, Lili
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-09
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Polyphenols, commonly contained in fruits and vegetables, have long been associated with a protective role against multiple diseases and adverse health effects.
Generally, in vitro and animal experiments have provided strong positive evidence, whereas evidence from in vivo and human epidemiological studies is not strong enough.
Most epidemiological studies to date use food frequency questionnaire based dietary intake estimations, which inevitably incur imprecision.
Biomarkers of polyphenol have the potential to complement and enhance current studies.
This review performed a literature search of all epidemiological studies or controlled clinical/intervention trials which employed biomarkers of exposure for polyphenols to help assess their anticarcinogenic role, using studies on green tea polyphenols as a study model.
Currently, studies on this topic are still limited; breast cancer and prostate cancer were the only widely studied cancer types.
Isoflavone is the only widely studied polyphenol.
In addition to associations between polyphenols and cancer risks, factors such as host genetic susceptibility, epigenetic modification, and gut microbiome patterns may also impact on the protective roles of polyphenols.
More evidence should be collected by utilizing biomarkers of exposure for polyphenols in future epidemiological studies before a clear conclusion can be made.
American Psychological Association (APA)
Wang, Jincheng& Tang, Lili& Wang, Jia-Sheng. 2015. Biomarkers of Dietary Polyphenols in Cancer Studies: Current Evidence and Beyond. Oxidative Medicine and Cellular Longevity،Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1075751
Modern Language Association (MLA)
Wang, Jincheng…[et al.]. Biomarkers of Dietary Polyphenols in Cancer Studies: Current Evidence and Beyond. Oxidative Medicine and Cellular Longevity No. 2015 (2015), pp.1-14.
https://search.emarefa.net/detail/BIM-1075751
American Medical Association (AMA)
Wang, Jincheng& Tang, Lili& Wang, Jia-Sheng. Biomarkers of Dietary Polyphenols in Cancer Studies: Current Evidence and Beyond. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2015, no. 2015, pp.1-14.
https://search.emarefa.net/detail/BIM-1075751
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075751