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Exercise Training and Calorie Restriction Influence the Metabolic Parameters in Ovariectomized Female Rats
Joint Authors
Varga, Csaba
Szalai, Zita
Csonka, Anett
Veszelka, Médea
Török, Szilvia
Daruka, Lejla
Kupai, Krisztina
Pósa, Anikó
Szabó, Renáta
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The estrogen deficiency after menopause leads to overweight or obesity, and physical exercise is one of the important modulators of this body weight gain.
Female Wistar rats underwent ovariectomy surgery (OVX) or sham operation (SO).
OVX and SO groups were randomized into new groups based on the voluntary physical activity (with or without running) and the type of diet for 12 weeks.
Rats were fed standard chow (CTRL), high triglyceride diet (HT), or restricted diet (CR).
The metabolic syndrome was assessed by measuring the body weight gain, the glucose sensitivity, and the levels of insulin, triglyceride, leptin, and aspartate aminotransferase transaminase (AST) and alanine aminotransferase (ALT).
The exercise training combined with the CR resulted in improvements in the glucose tolerance and the insulin sensitivity.
Plasma TG, AST, and ALT levels were significantly higher in OVX rats fed with HT but these high values were suppressed by exercise and CR.
Compared to SO animals, estrogen deprivation with HT caused a significant increase in leptin level.
Our data provide evidence that CR combined with voluntary physical exercise can be a very effective strategy to prevent the development of a metabolic syndrome induced by high calorie diet.
American Psychological Association (APA)
Pósa, Anikó& Szabó, Renáta& Kupai, Krisztina& Csonka, Anett& Szalai, Zita& Veszelka, Médea…[et al.]. 2015. Exercise Training and Calorie Restriction Influence the Metabolic Parameters in Ovariectomized Female Rats. Oxidative Medicine and Cellular Longevity،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1075770
Modern Language Association (MLA)
Pósa, Anikó…[et al.]. Exercise Training and Calorie Restriction Influence the Metabolic Parameters in Ovariectomized Female Rats. Oxidative Medicine and Cellular Longevity No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1075770
American Medical Association (AMA)
Pósa, Anikó& Szabó, Renáta& Kupai, Krisztina& Csonka, Anett& Szalai, Zita& Veszelka, Médea…[et al.]. Exercise Training and Calorie Restriction Influence the Metabolic Parameters in Ovariectomized Female Rats. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1075770
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075770