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Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans
Joint Authors
Abdelaziz, Kheira M.
Bonet-Costa, Vicent
Olaso, G.
Lopez-Grueso, R.
Gimeno-Mallench, L.
Mas-Bargues, C.
Gomez-Cabrera, M. C.
Inglés, Marta
Viña, Jose
Gambini, Juan
Borrás, Consuelo
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-28
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Plants containing resveratrol have been used effectively in traditional medicine for over 2000 years.
It can be found in some plants, fruits, and derivatives, such as red wine.
Therefore, it can be administered by either consuming these natural products or intaking nutraceutical pills.
Resveratrol exhibits a wide range of beneficial properties, and this may be due to its molecular structure, which endow resveratrol with the ability to bind to many biomolecules.
Among these properties its activity as an anticancer agent, a platelet antiaggregation agent, and an antioxidant, as well as its antiaging, antifrailty, anti-inflammatory, antiallergenic, and so forth activities, is worth highlighting.
These beneficial biological properties have been extensively studied in humans and animal models, both in vitro and in vivo.
The issue of bioavailability of resveratrol is of paramount importance and is determined by its rapid elimination and the fact that its absorption is highly effective, but the first hepatic step leaves little free resveratrol.
Clarifying aspects like stability and pharmacokinetics of resveratrol metabolites would be fundamental to understand and apply the therapeutic properties of resveratrol.
American Psychological Association (APA)
Gambini, Juan& Inglés, Marta& Olaso, G.& Lopez-Grueso, R.& Bonet-Costa, Vicent& Gimeno-Mallench, L.…[et al.]. 2015. Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans. Oxidative Medicine and Cellular Longevity،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1075790
Modern Language Association (MLA)
Gambini, Juan…[et al.]. Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans. Oxidative Medicine and Cellular Longevity No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1075790
American Medical Association (AMA)
Gambini, Juan& Inglés, Marta& Olaso, G.& Lopez-Grueso, R.& Bonet-Costa, Vicent& Gimeno-Mallench, L.…[et al.]. Properties of Resveratrol: In Vitro and In Vivo Studies about Metabolism, Bioavailability, and Biological Effects in Animal Models and Humans. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1075790
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075790