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Triptorelin in the Relief of Lower Urinary Tract Symptoms in Advanced Prostate Cancer Patients: The RESULT Study
Joint Authors
Peltier, Alexandre
De Ruyter, Vincent
Cabri, Patrick
van Velthoven, Roland
Aoun, Fouad
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
This prospective, noninterventional, open-label, multicentre, Belgian study assessed the prevalence of moderate to severe lower urinary tract symptoms (LUTS) in patients with locally advanced or metastatic prostate cancer scheduled to receive triptorelin therapy and its effects on LUTS were evaluated focusing on symptom relief and changes in quality of life (QOL) related to urinary symptoms (November 2006 to May 2010).
Inclusion criteria were age >18 years, histologically confirmed advanced or metastatic prostate cancer, and life expectancy ≥12 months.
Exclusion criteria were treatment with any LHRH analogue within the last 6 months or any other investigational agent within the last 3 months before study entry.
Patients who received one or more triptorelin doses and had one or more efficacy assessments were evaluated.
In total, 325 patients were included with a median age of 74 years (50 to 95 years).
Mean age at first diagnosis was 73±8 years.
Moderate (IPSS 8–19) to severe (IPSS ≥ 20) LUTS were observed in 62% of patients.
Triptorelin reduced LUTS severity.
This improvement was perceived within the first 24 weeks of treatment and was maintained after 48 weeks.
A decrease in PSA level was also observed.
American Psychological Association (APA)
Peltier, Alexandre& Aoun, Fouad& De Ruyter, Vincent& Cabri, Patrick& van Velthoven, Roland. 2015. Triptorelin in the Relief of Lower Urinary Tract Symptoms in Advanced Prostate Cancer Patients: The RESULT Study. Prostate Cancer،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1075843
Modern Language Association (MLA)
Peltier, Alexandre…[et al.]. Triptorelin in the Relief of Lower Urinary Tract Symptoms in Advanced Prostate Cancer Patients: The RESULT Study. Prostate Cancer No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1075843
American Medical Association (AMA)
Peltier, Alexandre& Aoun, Fouad& De Ruyter, Vincent& Cabri, Patrick& van Velthoven, Roland. Triptorelin in the Relief of Lower Urinary Tract Symptoms in Advanced Prostate Cancer Patients: The RESULT Study. Prostate Cancer. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1075843
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075843