The Effects of Uric Acid, Serum Vitamin D3, and Their Interaction on Parkinson’s Disease Severity
Joint Authors
Meamar, Rokhsareh
Shaabani, Pooria
Tabibian, Seyed Reza
Aghaye Ghazvini, Mohammad Reza
Feizi, Awat
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-24
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objectives.
In current study, the relationships between serum vitamin D3 levels and serum UA concentrations as well as their interaction with severity of PD were evaluated in a sample of Iranian PD patients.
Method.
In a cross sectional study at the one of the main referral hospitals in central region of Iran, during September to November 2011, 112 patients were recruited.
Severity of PD was evaluated sing H&R stages and UPDRS.
Results.
The Spearman rank correlation coefficient suggests the negative significant association between serum vitamin D3 and UPDRS in patients aged >62 (r=-0.34, P<0.05).
No statistically significant association was observed between the UA levels and severity of PD (represented by H&Y categories) in different levels of serum vitamin D3 not only in total sample but also in separate age and sex groups.
The linear regression coefficients suggested positive association between UA and serum vitamin D3 with UPDRSIII scores while negative relationship between UA and serum vitamin D3 interaction with UPDRSIII; however it was only statistically significant in age group ≤62 (P<0.05).
Conclusion.
Our study revealed a negative correlation between interaction of serum vitamin D3 and UA with severity of PD; other studies are required to confirm our findings.
American Psychological Association (APA)
Meamar, Rokhsareh& Shaabani, Pooria& Tabibian, Seyed Reza& Aghaye Ghazvini, Mohammad Reza& Feizi, Awat. 2015. The Effects of Uric Acid, Serum Vitamin D3, and Their Interaction on Parkinson’s Disease Severity. Parkinson’s Disease،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1075880
Modern Language Association (MLA)
Meamar, Rokhsareh…[et al.]. The Effects of Uric Acid, Serum Vitamin D3, and Their Interaction on Parkinson’s Disease Severity. Parkinson’s Disease No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1075880
American Medical Association (AMA)
Meamar, Rokhsareh& Shaabani, Pooria& Tabibian, Seyed Reza& Aghaye Ghazvini, Mohammad Reza& Feizi, Awat. The Effects of Uric Acid, Serum Vitamin D3, and Their Interaction on Parkinson’s Disease Severity. Parkinson’s Disease. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1075880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075880