Personality Changes after Deep Brain Stimulation in Parkinson’s Disease
Joint Authors
Aarsland, Dag
Haraldsen, Ira R.
Andersson, Stein
Pham, Uyen Ha Gia
Pripp, Are Hugo
Konglund, Ane Eidahl
Dietrichs, Espen
Malt, Ulrik Fredrik
Solbakk, Anne-Kristin
Skogseid, Inger-Marie
Toft, M.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objectives.
Deep brain stimulation of the subthalamic nucleus (STN-DBS) is a recognized therapy that improves motor symptoms in advanced Parkinson’s disease (PD).
However, little is known about its impact on personality.
To address this topic, we have assessed personality traits before and after STN-DBS in PD patients.
Methods.
Forty patients with advanced PD were assessed with the Temperament and Character Inventory (TCI): the Urgency, Premeditation, Perseverance, Sensation Seeking impulsive behaviour scale (UPPS), and the Neuroticism and Lie subscales of the Eysenck Personality Questionnaire (EPQ-N, EPQ-L) before surgery and after three months of STN-DBS.
Collateral information obtained from the UPPS was also reported.
Results.
Despite improvement in motor function and reduction in dopaminergic dosage patients reported lower score on the TCI Persistence and Self-Transcendence scales, after three months of STN-DBS, compared to baseline (P=0.006; P=0.024).
Relatives reported significantly increased scores on the UPPS Lack of Premeditation scale at follow-up (P=0.027).
Conclusion.
STN-DBS in PD patients is associated with personality changes in the direction of increased impulsivity.
American Psychological Association (APA)
Pham, Uyen Ha Gia& Solbakk, Anne-Kristin& Skogseid, Inger-Marie& Toft, M.& Pripp, Are Hugo& Konglund, Ane Eidahl…[et al.]. 2015. Personality Changes after Deep Brain Stimulation in Parkinson’s Disease. Parkinson’s Disease،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1075884
Modern Language Association (MLA)
Pham, Uyen Ha Gia…[et al.]. Personality Changes after Deep Brain Stimulation in Parkinson’s Disease. Parkinson’s Disease No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1075884
American Medical Association (AMA)
Pham, Uyen Ha Gia& Solbakk, Anne-Kristin& Skogseid, Inger-Marie& Toft, M.& Pripp, Are Hugo& Konglund, Ane Eidahl…[et al.]. Personality Changes after Deep Brain Stimulation in Parkinson’s Disease. Parkinson’s Disease. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1075884
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075884