Association between Community Ambulation Walking Patterns and Cognitive Function in Patients with Parkinson’s Disease: Further Insights into Motor-Cognitive Links
Joint Authors
Weiss, Aner
Hausdorff, Jeffrey M.
Giladi, Nir
Herman, Talia
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-29
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
Cognitive function is generally evaluated based on testing in the clinic, but this may not always reflect real-life function.
We tested whether parameters derived from long-term, continuous monitoring of gait are associated with cognitive function in patients with Parkinson’s disease (PD).
Methods.
107 patients with PD (age: 64.9 ± 9.3 yrs; UPDRS motor sum “off”: 40.4 ± 13.2; 25.23% women) wore a 3D accelerometer on their lower back for 3 days.
Computerized measures of global cognitive function, executive function, attention, and nonverbal memory were assessed.
Three-day acceleration derived measures included cadence, variability, bilateral coordination, and dynamic postural control.
Associations between the acceleration derived measures and cognitive function were determined.
Results.
Linear regression showed associations between vertical gait variability and cadence and between global cognitive score, attention, and executive function ( p ≤ 0.048 ).
Dynamic postural control was associated with global cognitive score and attention ( p ≤ 0.027 ).
Nonverbal memory was not associated with the acceleration-derived measures.
Conclusions.
These findings suggest that metrics derived from a 3-day worn body-fixed sensor reflect cognitive function, further supporting the idea that the gait pattern may be altered as cognition declines and that gait provides a window into cognitive function in patients with PD.
American Psychological Association (APA)
Weiss, Aner& Herman, Talia& Giladi, Nir& Hausdorff, Jeffrey M.. 2015. Association between Community Ambulation Walking Patterns and Cognitive Function in Patients with Parkinson’s Disease: Further Insights into Motor-Cognitive Links. Parkinson’s Disease،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1075892
Modern Language Association (MLA)
Weiss, Aner…[et al.]. Association between Community Ambulation Walking Patterns and Cognitive Function in Patients with Parkinson’s Disease: Further Insights into Motor-Cognitive Links. Parkinson’s Disease No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1075892
American Medical Association (AMA)
Weiss, Aner& Herman, Talia& Giladi, Nir& Hausdorff, Jeffrey M.. Association between Community Ambulation Walking Patterns and Cognitive Function in Patients with Parkinson’s Disease: Further Insights into Motor-Cognitive Links. Parkinson’s Disease. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1075892
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075892