The Role of α-Synuclein and LRRK2 in Tau Phosphorylation
Joint Authors
Takeda, Yuko
Ichikawa, Takafumi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-21
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
There is now a considerable body of experimental evidence that Parkinson’s disease arises through physiological interaction of causative molecules, leading to tau pathology.
In this review, we discuss the physiological role of α-synuclein and LRRK2 in the abnormal phosphorylation of tau.
In addition, as recent reports have indicated that heat shock proteins- (HSPs-) inducing drugs can help to ameliorate neurodegenerative diseases associated with tau pathology, we also discuss therapeutic strategies for PD focusing on inhibition of α-synuclein- and LRRK2-associated tau phosphorylation by HSPs.
American Psychological Association (APA)
Takeda, Yuko& Ichikawa, Takafumi. 2015. The Role of α-Synuclein and LRRK2 in Tau Phosphorylation. Parkinson’s Disease،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1075909
Modern Language Association (MLA)
Takeda, Yuko& Ichikawa, Takafumi. The Role of α-Synuclein and LRRK2 in Tau Phosphorylation. Parkinson’s Disease No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1075909
American Medical Association (AMA)
Takeda, Yuko& Ichikawa, Takafumi. The Role of α-Synuclein and LRRK2 in Tau Phosphorylation. Parkinson’s Disease. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1075909
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075909
