Clinical and Epidemiological Factors Associated with Mortality in Parkinson’s Disease in a Brazilian Cohort
Joint Authors
Rieder, Carlos R. M.
Fernandes, Gustavo Costa
Socal, Mariana Peixoto
Schuh, Artur Francisco Schumacher
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-27
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Prognosis of PD is variable.
Most studies show higher mortality rates in PD patients compared to the general population.
Clinical and epidemiologic factors predicting mortality are poorly understood.
Methods.
Clinical and epidemiologic features including patient history and physical, functional, and cognitive scores were collected from a hospital-based cohort of PD patients using standardized protocols and clinical scales.
Data on comorbidities and mortality were collected on follow-up.
Results.
During a mean follow-up of 4.71 years (range 1–10), 43 (20.9%) of the 206 patients died.
Those who died had higher mean age at disease onset than those still alive at the last follow-up (67.7 years versus 56.3 years; p<0.01).
In the univariate analysis, age at baseline was associated with decreased survival.
In the adjusted Cox proportional hazards model, age at disease onset and race/ethnicity were predictors of mortality.
Conclusions.
Late age at disease onset and advanced chronological age are associated with decreased survival.
Comorbidities and PD characteristics were not associated with decreased survival in our sample.
Race/ethnicity was found in our study to be associated with increased hazard of mortality.
Our findings indicate the importance of studying survival among different populations of PD patients.
American Psychological Association (APA)
Fernandes, Gustavo Costa& Socal, Mariana Peixoto& Schuh, Artur Francisco Schumacher& Rieder, Carlos R. M.. 2015. Clinical and Epidemiological Factors Associated with Mortality in Parkinson’s Disease in a Brazilian Cohort. Parkinson’s Disease،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075930
Modern Language Association (MLA)
Fernandes, Gustavo Costa…[et al.]. Clinical and Epidemiological Factors Associated with Mortality in Parkinson’s Disease in a Brazilian Cohort. Parkinson’s Disease No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1075930
American Medical Association (AMA)
Fernandes, Gustavo Costa& Socal, Mariana Peixoto& Schuh, Artur Francisco Schumacher& Rieder, Carlos R. M.. Clinical and Epidemiological Factors Associated with Mortality in Parkinson’s Disease in a Brazilian Cohort. Parkinson’s Disease. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1075930
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1075930