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Intra-Articular Synovial Sarcomas: Incidence and Differentiating Features from Localized Pigmented Villonodular Synovitis
Joint Authors
Brosjö, Otte
Nordemar, D.
Öberg, J.
Skorpil, M.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-24
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Purpose.
To determine the incidence of intra-articular synovial sarcomas and investigate if any radiological variables can differentiate them from localized (unifocal) pigmented villonodular synovitis (PVNS) and if multivariate data analysis could be used as a complementary clinical tool.
Methods.
Magnetic resonance images and radiographs of 7 cases of intra-articular synovial sarcomas and 14 cases of localized PVNS were blindedly reviewed.
Variables analyzed were size, extra-articular growth, tumor border, blooming, calcification, contrast media enhancement, effusion, bowl of grapes sign, triple signal intensity sign, synovial low signal intensity, synovitis, age, and gender.
Univariate and multivariate data analysis, the method of partial least squares-discriminant analysis (PLS-DA), were used.
Register data on all synovial sarcomas were extracted for comparison.
Results.
The incidence of intra-articular synovial sarcomas was 3%.
PLS-DA showed that age, effusion, size, and gender were the most important factors for discrimination between sarcomas and localized PVNS.
No sarcomas were misclassified as PVNS with PLS-DA, while some PVNS were misclassified as sarcomas.
Conclusions.
The most important variables in differentiating intra-articular sarcomas from localized PVNS were age, effusion, size, and gender.
Multivariate data analysis can be helpful as additive information to avoid a biopsy, if the tumor is classified as most likely being PVNS.
American Psychological Association (APA)
Nordemar, D.& Öberg, J.& Brosjö, Otte& Skorpil, M.. 2015. Intra-Articular Synovial Sarcomas: Incidence and Differentiating Features from Localized Pigmented Villonodular Synovitis. Complexity،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1076107
Modern Language Association (MLA)
Nordemar, D.…[et al.]. Intra-Articular Synovial Sarcomas: Incidence and Differentiating Features from Localized Pigmented Villonodular Synovitis. Complexity No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1076107
American Medical Association (AMA)
Nordemar, D.& Öberg, J.& Brosjö, Otte& Skorpil, M.. Intra-Articular Synovial Sarcomas: Incidence and Differentiating Features from Localized Pigmented Villonodular Synovitis. Complexity. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1076107
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076107