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Cell Therapy Augments Functional Recovery Subsequent to Spinal Cord Injury under Experimental Conditions
Joint Authors
Kumar, Sanjay
Sabapathy, Vikram
Tharion, George
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-09
Country of Publication
Egypt
No. of Pages
12
Abstract EN
The spinal cord injury leads to enervation of normal tissue homeostasis ultimately leading to paralysis.
Until now there is no proper cure for the treatment of spinal cord injury.
Recently, cell therapy in animal spinal cord injury models has shown some progress of recovery.
At present, clinical trials are under progress to evaluate the efficacy of cell transplantation for the treatment of spinal cord injury.
Different types of cells such as pluripotent stem cells derived neural cells, mesenchymal stromal cells, neural stem cells, glial cells are being tested in various spinal cord injury models.
In this review we highlight both the advances and lacuna in the field of spinal cord injury by discussing epidemiology, pathophysiology, molecular mechanism, and various cell therapy strategies employed in preclinical and clinical injury models and finally we discuss the limitations and ethical issues involved in cell therapy approach for treating spinal cord injury.
American Psychological Association (APA)
Sabapathy, Vikram& Tharion, George& Kumar, Sanjay. 2015. Cell Therapy Augments Functional Recovery Subsequent to Spinal Cord Injury under Experimental Conditions. Stem Cells International،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1076124
Modern Language Association (MLA)
Sabapathy, Vikram…[et al.]. Cell Therapy Augments Functional Recovery Subsequent to Spinal Cord Injury under Experimental Conditions. Stem Cells International No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1076124
American Medical Association (AMA)
Sabapathy, Vikram& Tharion, George& Kumar, Sanjay. Cell Therapy Augments Functional Recovery Subsequent to Spinal Cord Injury under Experimental Conditions. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1076124
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076124