Hematopoietic Stem and Immune Cells in Chronic HIV Infection
Joint Authors
Zhang, Jielin
Crumpacker, Clyde
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-02
Country of Publication
Egypt
No. of Pages
7
Abstract EN
Hematopoietic stem cell (HSC) belongs to multipotent adult somatic stem cells.
A single HSC can reconstitute the entire blood system via self-renewal, differentiation into all lineages of blood cells, and replenishment of cells lost due to attrition or disease in a person’s lifetime.
Although all blood and immune cells derive from HSC, immune cells, specifically immune memory cells, have the properties of HSC on self-renewal and differentiation into lineage effector cells responding to the invading pathogens.
Moreover, the interplay between immune memory cell and viral pathogen determines the course of a viral infection.
Here, we state our point of view on the role of blood stem and progenitor cell in chronic HIV infection, with a focus on memory CD4 T-cell in the context of HIV/AIDS eradication and cure.
American Psychological Association (APA)
Zhang, Jielin& Crumpacker, Clyde. 2015. Hematopoietic Stem and Immune Cells in Chronic HIV Infection. Stem Cells International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1076133
Modern Language Association (MLA)
Zhang, Jielin& Crumpacker, Clyde. Hematopoietic Stem and Immune Cells in Chronic HIV Infection. Stem Cells International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1076133
American Medical Association (AMA)
Zhang, Jielin& Crumpacker, Clyde. Hematopoietic Stem and Immune Cells in Chronic HIV Infection. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1076133
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076133