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In Vitro Studies of Bacterial Cellulose and Magnetic NanoparticlesSmart Nanocomposites for Efficient Chronic Wounds Healing
Joint Authors
Hermenean, Anca
Bunea, Mihaela-Cristina
Stanescu, Paul
Vasile, Eugenia
Casarica, Angela
Zaharia, Catalin
Iovu, Horia
Galateanu, Bianca
Marieta, Costache
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-28
Country of Publication
Egypt
No. of Pages
10
Abstract EN
The quality of life of patients with chronic wounds can be extremely poor and, therefore, over the past decades, great efforts have been made to develop efficient strategies to improve the healing process and the social impact associated with these conditions.
Cell based therapy, as a modern tissue engineering strategy, involves the design of 3D cell-scaffold bioconstructs obtained by preseeding drug loaded scaffolds with undifferentiated cells in order to achieve in situ functional de novo tissue.
This paper reports on the development of bionanocomposites based on bacterial cellulose and magnetic nanoparticles (magnetite) for efficient chronic wounds healing.
Composites were obtained directly in the cellulose bacterial culture medium by dispersing various amounts of magnetite nanoparticles during the biosynthesis process.
After purification and drying, the membranes were characterized by Raman spectroscopy and X-ray diffraction to reveal the presence of magnetite within the bacterial cellulose matrix.
Morphological investigation was employed through SEM and TEM analyses on bionanocomposites.
The biocompatibility of these innovative materials was studied in relation to human adipose derived stem cells in terms of cellular morphology, viability, and proliferation as well as scaffolds cytotoxic potential.
American Psychological Association (APA)
Galateanu, Bianca& Bunea, Mihaela-Cristina& Stanescu, Paul& Vasile, Eugenia& Casarica, Angela& Iovu, Horia…[et al.]. 2015. In Vitro Studies of Bacterial Cellulose and Magnetic NanoparticlesSmart Nanocomposites for Efficient Chronic Wounds Healing. Stem Cells International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1076151
Modern Language Association (MLA)
Galateanu, Bianca…[et al.]. In Vitro Studies of Bacterial Cellulose and Magnetic NanoparticlesSmart Nanocomposites for Efficient Chronic Wounds Healing. Stem Cells International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1076151
American Medical Association (AMA)
Galateanu, Bianca& Bunea, Mihaela-Cristina& Stanescu, Paul& Vasile, Eugenia& Casarica, Angela& Iovu, Horia…[et al.]. In Vitro Studies of Bacterial Cellulose and Magnetic NanoparticlesSmart Nanocomposites for Efficient Chronic Wounds Healing. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1076151
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076151