![](/images/graphics-bg.png)
Safety of Allogeneic Umbilical Cord Blood Stem Cells Therapy in Patients with Severe Cerebral Palsy: A Retrospective Study
Joint Authors
Feng, Mei
Lu, Aili
Gao, Hongxia
Qian, Caiwen
Zhang, Jun
Lin, Tongxiang
Zhao, Yuanqi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-08
Country of Publication
Egypt
No. of Pages
7
Abstract EN
This retrospective study aimed to assess the safety of patients with severe cerebral palsy (CP), who received allogeneic umbilical cord blood stem cells (UCBSCs) treatment from August 2009 to December 2012 in Guangdong Provincial Hospital of Chinese Medicine.
A total of 47 patients with average age of 5.85±6.12 years were evaluated in this study.
There was no significant association with allogeneic UCBSCs treatments found in the data of the laboratory index .
No casualties occurred.
Some adverse events during treatments were found in 26 (55.3%) patients, including fever (42.6%) and vomiting (21.2%).
Intrathecal infusion and the ages at the initiation of treatment (≤10 years old) were risk factors for the occurrence of adverse events by logistic regression analysis.
However, all adverse events disappeared after symptomatic treatment.
No treatment related serious adverse events were found in follow-up visits within 6 months.
In conclusion, allogeneic UCBSCs treatment was relatively safe for severe CP patients.
American Psychological Association (APA)
Feng, Mei& Lu, Aili& Gao, Hongxia& Qian, Caiwen& Zhang, Jun& Lin, Tongxiang…[et al.]. 2015. Safety of Allogeneic Umbilical Cord Blood Stem Cells Therapy in Patients with Severe Cerebral Palsy: A Retrospective Study. Stem Cells International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1076186
Modern Language Association (MLA)
Feng, Mei…[et al.]. Safety of Allogeneic Umbilical Cord Blood Stem Cells Therapy in Patients with Severe Cerebral Palsy: A Retrospective Study. Stem Cells International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1076186
American Medical Association (AMA)
Feng, Mei& Lu, Aili& Gao, Hongxia& Qian, Caiwen& Zhang, Jun& Lin, Tongxiang…[et al.]. Safety of Allogeneic Umbilical Cord Blood Stem Cells Therapy in Patients with Severe Cerebral Palsy: A Retrospective Study. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1076186
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076186