Regenerative Translation of Human Blood-Vessel-Derived MSC Precursors
Joint Authors
Chen, William C. W.
Huard, Johnny
Peault, Bruno
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-26
Country of Publication
Egypt
No. of Pages
11
Abstract EN
Mesenchymal stem/stromal cells (MSCs) represent a promising adult progenitor cell source for tissue repair and regeneration.
Their mysterious identity in situ has gradually been unveiled by the accumulating evidence indicating an association between adult multipotent stem/progenitor cells and vascular/perivascular niches.
Using immunohistochemistry and fluorescence-activated cell sorting, we and other groups have prospectively identified and purified subpopulations of multipotent precursor cells associated with the blood vessels within multiple human organs.
The three precursor subsets, myogenic endothelial cells (MECs), pericytes (PCs), and adventitial cells (ACs), are located, respectively, in the three structural tiers of typical blood vessels: intima, media, and adventitia.
MECs, PCs, and ACs have been extensively characterized in prior studies and are currently under investigation for their therapeutic potentials in preclinical animal models.
In this review, we will briefly discuss the identification, isolation, and characterization of these human blood-vessel-derived stem cells (hBVSCs) and summarize the current status of regenerative applications of hBVSC subsets.
American Psychological Association (APA)
Chen, William C. W.& Peault, Bruno& Huard, Johnny. 2015. Regenerative Translation of Human Blood-Vessel-Derived MSC Precursors. Stem Cells International،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1076195
Modern Language Association (MLA)
Chen, William C. W.…[et al.]. Regenerative Translation of Human Blood-Vessel-Derived MSC Precursors. Stem Cells International No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1076195
American Medical Association (AMA)
Chen, William C. W.& Peault, Bruno& Huard, Johnny. Regenerative Translation of Human Blood-Vessel-Derived MSC Precursors. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1076195
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076195