Advances and Prospects in Tissue-Engineered Meniscal Scaffolds for Meniscus Regeneration
Joint Authors
Guo, Weimin
Peng, Jiang
Wang, Ai-Yuan
Yuan, Mei
Zhang, Li
Chen, Ji-Feng
Xu, Wen-Jing
Guo, Quan-Yi
Wang, Yu
Shibi, Lu
Zhu, Yun
Yu, Changlong
Huang, Jingxiang
Yuan, Zhiguo
Sui, Xiang
Liu, Shuyun
Gao, Yue
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-25
Country of Publication
Egypt
No. of Pages
13
Abstract EN
The meniscus plays a crucial role in maintaining knee joint homoeostasis.
Meniscal lesions are relatively common in the knee joint and are typically categorized into various types.
However, it is difficult for inner avascular meniscal lesions to self-heal.
Untreated meniscal lesions lead to meniscal extrusions in the long-term and gradually trigger the development of knee osteoarthritis (OA).
The relationship between meniscal lesions and knee OA is complex.
Partial meniscectomy, which is the primary method to treat a meniscal injury, only relieves short-term pain; however, it does not prevent the development of knee OA.
Similarly, other current therapeutic strategies have intrinsic limitations in clinical practice.
Tissue engineering technology will probably address this challenge by reconstructing a meniscus possessing an integrated configuration with competent biomechanical capacity.
This review describes normal structure and biomechanical characteristics of the meniscus, discusses the relationship between meniscal lesions and knee OA, and summarizes the classifications and corresponding treatment strategies for meniscal lesions to understand meniscal regeneration from physiological and pathological perspectives.
Last, we present current advances in meniscal scaffolds and provide a number of prospects that will potentially benefit the development of meniscal regeneration methods.
American Psychological Association (APA)
Guo, Weimin& Liu, Shuyun& Zhu, Yun& Yu, Changlong& Shibi, Lu& Yuan, Mei…[et al.]. 2015. Advances and Prospects in Tissue-Engineered Meniscal Scaffolds for Meniscus Regeneration. Stem Cells International،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1076243
Modern Language Association (MLA)
Guo, Weimin…[et al.]. Advances and Prospects in Tissue-Engineered Meniscal Scaffolds for Meniscus Regeneration. Stem Cells International No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1076243
American Medical Association (AMA)
Guo, Weimin& Liu, Shuyun& Zhu, Yun& Yu, Changlong& Shibi, Lu& Yuan, Mei…[et al.]. Advances and Prospects in Tissue-Engineered Meniscal Scaffolds for Meniscus Regeneration. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1076243
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076243