Current Bioengineering Methods for Whole Kidney Regeneration
Joint Authors
Yokoo, Takashi
Yamanaka, Shuichiro
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-18
Country of Publication
Egypt
No. of Pages
10
Abstract EN
Kidney regeneration is likely to provide an inexhaustible source of tissues and organs for immunosuppression-free transplantation.
It is currently garnering considerable attention and might replace kidney dialysis as the ultimate therapeutic strategy for renal failure.
However, anatomical complications make kidney regeneration difficult.
Here, we review recent advances in the field of kidney regeneration, including (i) the directed differentiation of induced pluripotent stem cells/embryonic stem cells into kidney cells; (ii) blastocyst decomplementation; (iii) use of a decellularized cadaveric scaffold; (iv) embryonic organ transplantation; and (v) use of a nephrogenic niche for growing xenoembryos for de novo kidney regeneration from stem cells.
All these approaches represent potentially promising therapeutic strategies for the treatment of patients with chronic kidney disease.
Although many obstacles to kidney regeneration remain, we hope that innovative strategies and reliable research will ultimately allow the restoration of renal function in patients with end-stage kidney disease.
American Psychological Association (APA)
Yamanaka, Shuichiro& Yokoo, Takashi. 2015. Current Bioengineering Methods for Whole Kidney Regeneration. Stem Cells International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1076334
Modern Language Association (MLA)
Yamanaka, Shuichiro& Yokoo, Takashi. Current Bioengineering Methods for Whole Kidney Regeneration. Stem Cells International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1076334
American Medical Association (AMA)
Yamanaka, Shuichiro& Yokoo, Takashi. Current Bioengineering Methods for Whole Kidney Regeneration. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1076334
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076334