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Cell Therapy in Patients with Critical Limb Ischemia
Joint Authors
de Franciscis, Stefano
Amato, Bruno
Amato, Maurizio
Grande, Raffaele
Butrico, Lucia
Compagna, Rita
Massa, Salvatore
Serra, Raffaele
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-02
Country of Publication
Egypt
No. of Pages
13
Abstract EN
Critical limb ischemia (CLI) represents the most advanced stage of peripheral arterial obstructive disease (PAOD) with a severe obstruction of the arteries which markedly reduces blood flow to the extremities and has progressed to the point of severe rest pain and/or even tissue loss.
Recent therapeutic strategies have focused on restoring this balance in favor of tissue survival using exogenous molecular and cellular agents to promote regeneration of the vasculature.
These are based on stimulation of angiogenesis by extracellular and cellular components.
This review article carries out a systematic analysis of the most recent scientific literature on the application of stem cells in patients with CLI.
The results obtained from the detailed analysis of the recent literature data have confirmed the beneficial role of cell therapy in reducing the rate of major amputations in patients with CLI and improving their quality of life.
American Psychological Association (APA)
Compagna, Rita& Amato, Bruno& Massa, Salvatore& Amato, Maurizio& Grande, Raffaele& Butrico, Lucia…[et al.]. 2015. Cell Therapy in Patients with Critical Limb Ischemia. Stem Cells International،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1076387
Modern Language Association (MLA)
Compagna, Rita…[et al.]. Cell Therapy in Patients with Critical Limb Ischemia. Stem Cells International No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1076387
American Medical Association (AMA)
Compagna, Rita& Amato, Bruno& Massa, Salvatore& Amato, Maurizio& Grande, Raffaele& Butrico, Lucia…[et al.]. Cell Therapy in Patients with Critical Limb Ischemia. Stem Cells International. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1076387
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076387