Effects of Salvadora persica Extract on the Hematological and Biochemical Alterations against Immobilization-Induced Rats
Joint Authors
Ramadan, Kholoud S.
Alshamrani, Salha A.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A total of 24 rats were divided into 4 groups: control, stress, extract alone, and stress + extract (n=6 each), for total 21 days of treatment.
The immobilization stress was induced in rats by putting them in 20 cm × 7 cm plastic tubes for 2 h/day for 21 days.
Rats were postorally treated with Salvadora persica at a dose of 900 mg/kg body weight via intragastric intubations.
At the end of the test period, hematological and biochemical parameters were determined in blood and serum samples with determination of vital organs weights.
The vital organ weights were not significantly affected in stressed rats as compared to control rats.
Compared to the control group, the stress treated group showed significances in several hematological parameters, including decreases in WBC, RBC, and PLT counts.
Furthermore, in comparison to the control group, the stress group showed significantly increased blood glucose, serum total cholesterol, LDL-cholesterol, and triacylglycerols levels and decreased HDL-cholesterol level.
The hematological and biochemical parameters in the stress + extract treated group were approximately similar to control group.
The SP extract restored the changes observed following stress treatment.
American Psychological Association (APA)
Ramadan, Kholoud S.& Alshamrani, Salha A.. 2015. Effects of Salvadora persica Extract on the Hematological and Biochemical Alterations against Immobilization-Induced Rats. Scientifica،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1076435
Modern Language Association (MLA)
Ramadan, Kholoud S.& Alshamrani, Salha A.. Effects of Salvadora persica Extract on the Hematological and Biochemical Alterations against Immobilization-Induced Rats. Scientifica No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1076435
American Medical Association (AMA)
Ramadan, Kholoud S.& Alshamrani, Salha A.. Effects of Salvadora persica Extract on the Hematological and Biochemical Alterations against Immobilization-Induced Rats. Scientifica. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1076435
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076435