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Evaluation of Factor VIII as a Risk Factor in Indian Patients with DVT
Joint Authors
Agarwal, Indira
Hazra, Darpanarayan
Sen, Indrani
Stephen, Edwin
Nair, Sukesh Chandran
Mammen, Joy
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-01
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
Elevated factor VIII population in the Indian population has not been studied as a possible risk factor for deep vein thrombosis (DVT).
High factor VIII level is considered a predisposing factor for DVT and its recurrence.
However it is known to vary between populations and its exact role in the etiopathogenesis of thrombophilia remains unknown.
Material and Methods.
Factor VIII levels of patients with DVT who had undergone a prothrombotic workup as a part of their workup was compared to normal age matched controls in a 1 : 3 ratio.
Results.
There were 75 patients with DVT who had undergone a prothrombotic workup in the course of their treatment for lower limb DVT.
In these, 64% had levels of factor VIII more than 150 as compared to 63% of normal controls (p>0.05, not significant).
Conclusion.
Elevated factor VIII in the Indians may not be associated with the same thrombotic risk as seen in the West.
We find a variation in the levels of factor VIII with a different “normal” than what is reported in other populations.
This needs further study to elucidate the role of factor VIII in the evaluation and treatment of thrombophilia.
American Psychological Association (APA)
Hazra, Darpanarayan& Sen, Indrani& Stephen, Edwin& Agarwal, Indira& Nair, Sukesh Chandran& Mammen, Joy. 2015. Evaluation of Factor VIII as a Risk Factor in Indian Patients with DVT. Surgery Research and Practice،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1076578
Modern Language Association (MLA)
Hazra, Darpanarayan…[et al.]. Evaluation of Factor VIII as a Risk Factor in Indian Patients with DVT. Surgery Research and Practice No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1076578
American Medical Association (AMA)
Hazra, Darpanarayan& Sen, Indrani& Stephen, Edwin& Agarwal, Indira& Nair, Sukesh Chandran& Mammen, Joy. Evaluation of Factor VIII as a Risk Factor in Indian Patients with DVT. Surgery Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1076578
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1076578