The effect of marjoram and cocoa on oxidative stress caused by ovariectomy in rats

Other Title(s)

تأثير البردقوش و الكاكاو على الإجهاد التأكسدي الناتج عن استئصال المبايض لدى الفئران

Joint Authors

Ibrahim, Marwah Izz al-Din
Fahmi, Tasnim Subhi

Source

المجلة العلمية للدراسات و البحوث التربوية و النوعية

Publisher

Benha University Faculty of Specific Education

Publication Date

2020-02-29

Country of Publication

Egypt

No. of Pages

23

Main Subjects

Educational Sciences

Topics

• Oxidative Stress

English Abstract

has known that postmenopausal life affects aoxidative status for bodies.

Ovariectomy in rats was the same effect on postmenopausal for several organs.

In the present study it can be hypothesized that dietary high in antioxidant such as marjoram and cocoa could protect against weakness and oxidative stress following ovariectomy in rats.

Thirty-five female albino rats, ten 3- month old weighing (120 ± 10 g) were used.

The first main group (n=7) was fed on the basal diet (-ve control).

The second main group (n = 22) was subject to ovariectomy surgery to induced oxidative stress.

Then rats were divided into 4 subgroups (7 rats each).

Subgroup 1 was fed on basal diet (+ve control).

Subgroup 2, 3were fed on the basal diet and supplemented with dried marjoram , cocoa at the level of 10٪, respectively for three month.

Subgroup 4 were fed on the basal diet and supplemented with mixed (5 % Marjoram+5٪ Cocoa ) for three month.

Oxidative status was evaluated by SOD, Catalase, GSH, and MDA in Liver, Heart and Kidney tissues.

The marjoramtreated rats result showed significantly P<0.05 increased level of antioxidant enzymes in liver heart and kidney tissues compared to positive control.

The results of antioxidant enzyme for kidney tissues showed significant increased for SOD, CAT and GSH for group treated cocoa 10٪ compared to positive control.

Also, It could be notice that cocoa 10٪ group and group treated with mixed (cocoa 5٪ + marjoram 5٪) showed significantly P<0.05 highest level of SOD, CAT and GSH in liver and heart tissue.

Also, the presented work showed MDA status decreased significantly in heart, liver, kidney tissues for all treated groups compared to (+ve control).

Finally, consumption of coca and marjoram has a protective role against oxidative stress caused by ovariectomy surgery, it is suggested to use these components especially cocoa through postmenopausal life.

Data Type

Conference Papers

Record ID

BIM-1078447

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