Novel PETSPECT Probes for Imaging of Tau in Alzheimer’s Disease
Joint Authors
Watanabe, Hiroyuki
Saji, Hideo
Ono, Masahiro
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
As the world’s population ages, the number of patients with Alzheimer’s disease (AD) is predicted to increase rapidly.
The presence of neurofibrillary tangles (NFTs), composed of hyperphosphorylated tau protein, is one of the neuropathological hallmarks of AD brain.
Since the presence of NFTs is well correlated with neurodegeneration and cognitive decline in AD, imaging of tau using positron emission tomography (PET) and single-photon emission computed tomography (SPECT) is useful for presymptomatic diagnosis and monitoring of the progression of AD.
Therefore, novel PET/SPECT probes for the imaging of tau have been developed.
More recently, several probes were tested clinically and evaluated for their utility.
This paper reviews the current state of research on the development and evaluation of PET/SPECT probes for the imaging of tau in AD brain.
American Psychological Association (APA)
Watanabe, Hiroyuki& Ono, Masahiro& Saji, Hideo. 2015. Novel PETSPECT Probes for Imaging of Tau in Alzheimer’s Disease. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1078475
Modern Language Association (MLA)
Watanabe, Hiroyuki…[et al.]. Novel PETSPECT Probes for Imaging of Tau in Alzheimer’s Disease. The Scientific World Journal No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1078475
American Medical Association (AMA)
Watanabe, Hiroyuki& Ono, Masahiro& Saji, Hideo. Novel PETSPECT Probes for Imaging of Tau in Alzheimer’s Disease. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1078475
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1078475