Conjunctival Flap Covering Combined with Antiviral and Steroid Therapy for Severe Herpes Simplex Virus Necrotizing Stromal Keratitis
Joint Authors
Gao, Hua
Jia, Yanni
Shi, Weiyun
Li, Suxia
Tan, Yaohong
Wang, Ting
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-15
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Medicine
Information Technology and Computer Science
Abstract EN
Herpes simplex virus (HSV) necrotizing stromal keratitis is a common type of herpetic stromal keratitis (HSK).
Antiviral medication alone cannot control the disease, and corticosteroid eye drops may aggravate the ulcer and result in corneal perforation.
Amniotic membrane transplantation effectively treats superficial corneal ulcer resulting from necrotizing stromal HSK.
However, the efficacy of this approach seems to be limited for more serious cases.
This study presented the clinical treatment of severe HSV necrotizing stromal keratitis (ulcer depth greater than half of the corneal stroma) by conjunctival flap covering surgery in 25 patients (25 eyes) combined with antivirus and corticosteroid treatment at Shandong Eye Hospital from January 2007 to December 2013.
Clinical results showed that the mean best spectacle-corrected visual acuity improved from preoperative 20/333 to postoperative 20/40 (P<0.05).
All patients recovered ocular surface stabilization.
There was recurrence in two eyes, which was cured with antiviral medication.
Conjunctival flap covering combined with antivirus and corticosteroid treatment is effective in treating severe HSV necrotizing stromal keratitis.
American Psychological Association (APA)
Gao, Hua& Jia, Yanni& Li, Suxia& Wang, Ting& Tan, Yaohong& Shi, Weiyun. 2015. Conjunctival Flap Covering Combined with Antiviral and Steroid Therapy for Severe Herpes Simplex Virus Necrotizing Stromal Keratitis. The Scientific World Journal،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1078891
Modern Language Association (MLA)
Gao, Hua…[et al.]. Conjunctival Flap Covering Combined with Antiviral and Steroid Therapy for Severe Herpes Simplex Virus Necrotizing Stromal Keratitis. The Scientific World Journal No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1078891
American Medical Association (AMA)
Gao, Hua& Jia, Yanni& Li, Suxia& Wang, Ting& Tan, Yaohong& Shi, Weiyun. Conjunctival Flap Covering Combined with Antiviral and Steroid Therapy for Severe Herpes Simplex Virus Necrotizing Stromal Keratitis. The Scientific World Journal. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1078891
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1078891