Effect of antipsychotics on bone mineral density in autistic children

Abstract EN

Background: The prevalence of fractures in autism spectrum disorder (ASD) appear to be on the rise, we assessed variables as Antipsvchotics used in ASD treatment which may have an effect on bone mineral density.

BMD is measured with dual energy X- ray absorptiometry (DEXA).

Objective: The present study investigates the effect of Antipsychotics on bone mineral density in ASD children.

Patients and methods: 44 Participants were randomly chosen 36 boys and 8 girls, age ranged 3- 9 years old, and they were classified into 3 groups.

First group: 20 Autistic children under Antipsychotic.

Second group: 16 Autistic children didn’t receive medication.

Third group: 8 Normal children.

Result: The study revealed that in Group 1: 65% had no osteopenia and 35% had osteopenia.

Group 2: 50% had no osteopenia and 50% had osteopenia.

Group 3: 75% had no osteopenia and25% had osteopenia.

Conclusion: Antipsychotics had minimal effect on bone mineral density.