Investigation of cytotoxic effects of dichanthium annulatum f. and paspalum distichum L. on cell line SR. (Lymphoma) and L20B (Murine fibroblast)
Joint Authors
Shamran, Dhifaf Jabbar
Mahmud, Muhammad Radwan
Manshud, Mustafa Abd
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 26, Issue 3 (31 Mar. 2018), pp.184-190, 7 p.
Publisher
Publication Date
2018-03-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
D.
Annulatum F.
and P.
Distichum L., are grasses belongs to Poaceae family, they grow without any effort in the western plateau of Iraq in general and particulary in the southern part, located in the province of Muthanna.
These grasses are commonly used as a forage for livestock.
The present study was designed to evaluate the cytotoxic effect of D.
Annulatum F.
and P.
Distichum L.
methanolic extracts in vitro by using MTT assay (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) on two cell lines (SR and L20B) by using different concentrations (3.125, 6.25, 12.5, 25, 50, 100 and 200 μg/ml) for an incubation period of 24 hours.
We found cytotoxic effect for methanolic extract of D.
Annulatum F.
against SR cell line in low concentrations (3.125, 6.25μg/ml) which was (55%, 46%), and against the L20B cell line was (60%, 59%) in the same concentrations.
Regarding methanolic extract of P.
Distichum L.
the best effect was found with the lower concentrations which was (45%,44%) against SR and (49%,48%) against L20B.
In conclusion, the two grasses have a good potential anticancer effects.
American Psychological Association (APA)
Shamran, Dhifaf Jabbar& Mahmud, Muhammad Radwan& Manshud, Mustafa Abd. 2018. Investigation of cytotoxic effects of dichanthium annulatum f. and paspalum distichum L. on cell line SR. (Lymphoma) and L20B (Murine fibroblast). Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 26, no. 3, pp.184-190.
https://search.emarefa.net/detail/BIM-1093597
Modern Language Association (MLA)
Shamran, Dhifaf Jabbar…[et al.]. Investigation of cytotoxic effects of dichanthium annulatum f. and paspalum distichum L. on cell line SR. (Lymphoma) and L20B (Murine fibroblast). Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 26, no. 3 (2018), pp.184-190.
https://search.emarefa.net/detail/BIM-1093597
American Medical Association (AMA)
Shamran, Dhifaf Jabbar& Mahmud, Muhammad Radwan& Manshud, Mustafa Abd. Investigation of cytotoxic effects of dichanthium annulatum f. and paspalum distichum L. on cell line SR. (Lymphoma) and L20B (Murine fibroblast). Journal of Babylon University : Journal of Applied and Pure Sciences. 2018. Vol. 26, no. 3, pp.184-190.
https://search.emarefa.net/detail/BIM-1093597
Data Type
Journal Articles
Language
English
Notes
Text in English ; abstracts in English and Arabic.
Record ID
BIM-1093597