The correlation between vitamin d and clinical implications for obesity-related type 2 diabetes mellitus
Other Title(s)
العلاقة بين فيتامين D و التأثيرات السريرية المرتبطة بالسمنة و مرض السكري من النوع الثاني
Joint Authors
Hashim, Rasha Karim
Sulayman, Tibah Dawud
Ali, Intisar Shakir
al-Khalidi, Nur Thair Tahir
Ahmad, Hind Shakir
Source
Journal of Biotechnology Research Center
Issue
Vol. 14, Issue 1 (30 Jun. 2020), pp.39-46, 8 p.
Publisher
al-Nahrain University Biotechnology Research Center
Publication Date
2020-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
- Vitamin D
- Diabetes
- Vitamin D 3
- Glucose
- Body mass index
- Type 2 diabetes
- Glycosylated hemoglobin
- Insulin resistance
Abstract EN
Background: Obesity and type 2 diabetes have both rapidly raised during the last periods and are ongoing to increase at a disturbing rate universal.
Several clinical and epidemiological researches demonstrated a reverse association between circulating vitamin D levels, central adiposity and the progress of insulin resistance and diabetes.
Objective: The target of this work was to elucidate the complex role of vitamin D and the clinical implications of diabetes on metabolic defects related with obesity.
Subjects and Methods: This study encompassed 90 diabetic patients (45 obese and 45 non obese) who were attending the National Diabetic Center/ Al-Mustansiriyah University during the period from June 2019 to January 2020; their age range was (35-60) years.
All participant underwent clinical and biochemical examinations.
Results: A substantial rise (p= 0.01) in waist/hip ratio, body mass index, fasting serum glucose, total cholesterol, triacylglycerol, and low density lipoprotein cholesterol in obese diabetic patients as paralleled to non-obese group.
Moreover, there was an elevation in glycated hemoglobin, serum insulin, and homeostasis model assessment for insulin resistance in obese group, but it was not significant.
A substantial decrease (p= 0.01) in serum high density lipoprotein cholesterol and vitamin D3 were detected in obese diabetic patients as paralleled to non-obese group.
Also, obese diabetic patients had the higher percent (61% ) of D3 deficiency as paralleled to non-obese patients.
Conclusions: In the present study, it is found that there is significant increase in blood sugar in the individuals with decreased vitamin D levels, which was related with insulin resistance, decreased β-cell function, and obesity.
American Psychological Association (APA)
al-Khalidi, Nur Thair Tahir& Ahmad, Hind Shakir& Hashim, Rasha Karim& Sulayman, Tibah Dawud& Ali, Intisar Shakir. 2020. The correlation between vitamin d and clinical implications for obesity-related type 2 diabetes mellitus. Journal of Biotechnology Research Center،Vol. 14, no. 1, pp.39-46.
https://search.emarefa.net/detail/BIM-1093921
Modern Language Association (MLA)
al-Khalidi, Nur Thair Tahir…[et al.]. The correlation between vitamin d and clinical implications for obesity-related type 2 diabetes mellitus. Journal of Biotechnology Research Center Vol. 14, no. 1 (2020), pp.39-46.
https://search.emarefa.net/detail/BIM-1093921
American Medical Association (AMA)
al-Khalidi, Nur Thair Tahir& Ahmad, Hind Shakir& Hashim, Rasha Karim& Sulayman, Tibah Dawud& Ali, Intisar Shakir. The correlation between vitamin d and clinical implications for obesity-related type 2 diabetes mellitus. Journal of Biotechnology Research Center. 2020. Vol. 14, no. 1, pp.39-46.
https://search.emarefa.net/detail/BIM-1093921
Data Type
Journal Articles
Language
English
Notes
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Record ID
BIM-1093921