Comparison of the possible side effects of cyclosporine and tacrolimus on renal function in kidney transplant patients
Other Title(s)
مقارنة الآثار الجانبية المحتملة للسيكلوسبورين و التاكروليموس على وظائف الكلى في مرضى زراعة الكلى
Author
Abd al-Bari, Muhammad Abd al-Muttalib
Source
Journal of Biotechnology Research Center
Issue
Vol. 13, Issue 2 (31 Dec. 2019), pp.45-51, 7 p.
Publisher
al-Nahrain University Biotechnology Research Center
Publication Date
2019-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract EN
Background: Cyclosporine and Tacrolimus are two main immunosuppressants of kidney transplant patients and are commonly used in hospitals with renal transplantation.
Aim of the study: The goal of this study is to demonstrate potential harmful effects, not only from kidney failure as a disease, but also the use of immunosuppressants before and after renal transplants.
Materials and Methods: An analysis of tacrolimus or cyclosporine immunosuppressive regimes has been conducted in Baghdad hospital using data from patients with kidney transplants.
The study excluded patients who received other types of immune suppressant drugs, and those who switched from cyclosporine to tacrolimus.
Conclusion: Effectiveness and side effects should be tested in kidney transplantation patients with cyclosporin and tacrolimus and other immunosuppressive medications, tacrolimus treated patient has shown an increase in glucose level and decrease in WBC, hemoglobin and calcium level in comparing to cyclosporine treated group.
This finding may allow scientists and physicians to make a better choice between immunosuppressive drugs according to the patient's medical Background: Cyclosporine and Tacrolimus are two main immunosuppressants of kidney transplant patients and are commonly used in hospitals with renal transplantation.
Aim of the study: The goal of this study is to demonstrate potential harmful effects, not only from kidney failure as a disease, but also the use of immunosuppressants before and after renal transplants.
Materials and Methods: An analysis of tacrolimus or cyclosporine immunosuppressive regimes has been conducted in Baghdad hospital using data from patients with kidney transplants.
The study excluded patients who received other types of immune suppressant drugs, and those who switched from cyclosporine to tacrolimus.
Conclusion: Effectiveness and side effects should be tested in kidney transplantation patients with cyclosporin and tacrolimus and other immunosuppressive medications, tacrolimus treated patient has shown an increase in glucose level and decrease in WBC, hemoglobin and calcium level in comparing to cyclosporine treated group.
This finding may allow scientists and physicians to make a better choice between immunosuppressive drugs according to the patient's medical condition.
American Psychological Association (APA)
Abd al-Bari, Muhammad Abd al-Muttalib. 2019. Comparison of the possible side effects of cyclosporine and tacrolimus on renal function in kidney transplant patients. Journal of Biotechnology Research Center،Vol. 13, no. 2, pp.45-51.
https://search.emarefa.net/detail/BIM-1093932
Modern Language Association (MLA)
Abd al-Bari, Muhammad Abd al-Muttalib. Comparison of the possible side effects of cyclosporine and tacrolimus on renal function in kidney transplant patients. Journal of Biotechnology Research Center Vol. 13, no. 2 (2019), pp.45-51.
https://search.emarefa.net/detail/BIM-1093932
American Medical Association (AMA)
Abd al-Bari, Muhammad Abd al-Muttalib. Comparison of the possible side effects of cyclosporine and tacrolimus on renal function in kidney transplant patients. Journal of Biotechnology Research Center. 2019. Vol. 13, no. 2, pp.45-51.
https://search.emarefa.net/detail/BIM-1093932
Data Type
Journal Articles
Language
English
Notes
-
Record ID
BIM-1093932