Genetic analysis of dxs101and dxs6807 short tandem repeat (X-STR) in samples of Iraqi Arab male population
Other Title(s)
التحليل الوراثي Dxs101And Dxs6807 للتكرارات المترادفة القصيرة ( X-STR) في عينات من السكان الذكور العراقيين العرب
Joint Authors
Khalifah, Haydar Allawi
al-Tamimi, Zayd Nasif Abbas
al-Awadi, Salwa Jabir Abd Allah
Source
Journal of Biotechnology Research Center
Issue
Vol. 14, Issue 1 (30 Jun. 2020), pp.34-38, 5 p.
Publisher
al-Nahrain University Biotechnology Research Center
Publication Date
2020-06-30
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract AR
لقد أكدت التكرارات الترادفية القصيرة للكروموسومات X (X-STRs) أن تكون مفيدة ودورا خاصا في اختبار العلاقة المعقدة.
DXS6807 المعروف باسم تعدد الأشكال رباعي النيوكليوتيدات يمثل ثمانية أليلات بطول 251-275 زوجا قاعديا.
يقع DXS6807 في XP 22.2 على مسافة وراثية تزيد عن 87 و 151 سنتيمورغان من الكروموسوم.
X DXS101 يقع من 104.9 إلى 121 سنتيمورغان من (Xp-tel) الطرفي المطابق للموضع الوراثي الخلوي في Xq21.33 – Xq22.3.
.
الهدف من الدراسة: التحقيق و دراسة الترددات للايلات للمواقع المترادفة DXS101 DXS6807 للمعلمات و خصائصها الجنائية و الوراثية في للذكور العرب العراقيين.
طريقة العمل: تتكون الدراسة التي تشمل مئتين من الذكور العرب الاصحاء من مناطق مختلفة من مدينة بغداد للذكور تتراوح اعمارهم من 20 الى 50 سنة.
تم استخلاص الحامض النووي من عينات الدم بنجاح.
Abstract EN
Back ground: X-chromosomal short tandem repeats (X-STRs) have assured to be informative and particular role in complex relationship testing.
DXS6807 known as tetra nucleotides polymorphism representing eight alleles of 251-275 bp in length.
DXS6807 is located in, at XP 22.2, at a genetic distance of more than 87 and 151 Cm of X-chromosome.
DXS101 is located104.9–121 cM from the Xp-telomere (Xp-tel) corresponding to cytogenetic position in Xq21.33–Xq22.3.
Objective: The aim of this present study investigates the allele frequency of two markers DXS101, DXS6807 and forensic efficiency parameters for sample of Arabic Iraqi males.
Material and methods: The population of this study includes 200 males apparently healthy unrelated participants from different region of Baghdad city, their ages ranged between (20-50) years.
The Genomic DNA extracted and purified successfully from blood samples.
Results: The forensic efficiency parameters result for these markers were following: polymorphism information content (PIC) of 0.834708, power of discrimination (PD) in male 0.851750, Power of exclusion (PE) 0.698316, MEC Krüger0.511679, MEC Kishida 0.694890.
The forensic efficiency parameters analyzing from Arabic population were Power of discrimination (PD) = 0.73405, Polymorphism information content (PIC) =0.69489, Power of exclusion (PE) =0.482879.
MEC Krüger =0.511679, MEC Kishida = 0.694890.
Conclusions: The information provided establish this X-linked microsatellite marker as a valuable strategy for forensic application.
DXS101is and DXS6807 recently consider more stable and suitable forensic markers for forensic application.
American Psychological Association (APA)
Khalifah, Haydar Allawi& al-Awadi, Salwa Jabir Abd Allah& al-Tamimi, Zayd Nasif Abbas. 2020. Genetic analysis of dxs101and dxs6807 short tandem repeat (X-STR) in samples of Iraqi Arab male population. Journal of Biotechnology Research Center،Vol. 14, no. 1, pp.34-38.
https://search.emarefa.net/detail/BIM-1093950
Modern Language Association (MLA)
al-Awadi, Salwa Jabir Abd Allah…[et al.]. Genetic analysis of dxs101and dxs6807 short tandem repeat (X-STR) in samples of Iraqi Arab male population. Journal of Biotechnology Research Center Vol. 14, no. 1 (2020), pp.34-38.
https://search.emarefa.net/detail/BIM-1093950
American Medical Association (AMA)
Khalifah, Haydar Allawi& al-Awadi, Salwa Jabir Abd Allah& al-Tamimi, Zayd Nasif Abbas. Genetic analysis of dxs101and dxs6807 short tandem repeat (X-STR) in samples of Iraqi Arab male population. Journal of Biotechnology Research Center. 2020. Vol. 14, no. 1, pp.34-38.
https://search.emarefa.net/detail/BIM-1093950
Data Type
Journal Articles
Language
English
Notes
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Record ID
BIM-1093950