Preparation, characterization of a new cis-iodoplatin and Cis-carboplatin complexes and study there spectral, physical and pharmaceutical properties
Joint Authors
Hasan, Sama Muhammad
Awdah, Sadun A.
Abd al-Husayn, Jasim Muhammad
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 27, Issue 1 (28 Feb. 2019), pp.146-163, 18 p.
Publisher
Publication Date
2019-02-28
Country of Publication
Iraq
No. of Pages
18
Main Subjects
Topics
Abstract AR
يتضمن هذا البحث تحضير معقد جديد للسز-بالتين بصيغة اآليودين ) Iodoplatin – Cis ) وكذلك معقدين جديدين cis [ Pt (4- aminoantipyrine) (NH3)2]I2 و cis [Pt(aminosalicylicacid)(NH3)2] I : و هما كاربوبالتين-للسز و اللذان يمكن ان يستخدما كعقاقير ضد السرطان، و قد حضرا باستخدام الليكاندات العضوية : acid salicylic amino-4 وantipyrine amino-4 .
شخصت هذه المعقدات باستخدام التقنيات الطيفية : Vis–UV و FTIR و XRD و HNMR 1 .
و قد درست تأثير التركيز و درجة الحرارة على التوصيلية الكهربائية لمحاليل هذه المعقدات.
و قد حدد تاريخ انتهاء الصالحية (عمر النصف( لمحاليل هذه المعقدات في ظروف درجة الحرارة 35 و20 درجة مئوية.
Abstract EN
This search includes preparation of new cis–platin, in the form of iodin, and new two cis - carboplatin complexes {cis [Pt(4-aminoantipyrine) (NH3)2]I2 and cis[Pt (aminosalicylicacid) (NH3)2]I}, which used as anti - cancer drugs, they are prepared by using the organic ligands 4-amino salicylic acid and 4-amino anti pyrine.
These complexes were characterized by using UV–Vis., FTIR, XRD and 1HNMR spectroscopic techniques .
The effect of the concentration and the temperature on the molar electrical conductivity of its solutions were studied.
The expiry date (half-life) for the solutions of the complexes in the circumstances at the degrees (350C) and (20 0C) was determined.
American Psychological Association (APA)
Abd al-Husayn, Jasim Muhammad& Awdah, Sadun A.& Hasan, Sama Muhammad. 2019. Preparation, characterization of a new cis-iodoplatin and Cis-carboplatin complexes and study there spectral, physical and pharmaceutical properties. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 27, no. 1, pp.146-163.
https://search.emarefa.net/detail/BIM-1094632
Modern Language Association (MLA)
Abd al-Husayn, Jasim Muhammad…[et al.]. Preparation, characterization of a new cis-iodoplatin and Cis-carboplatin complexes and study there spectral, physical and pharmaceutical properties. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 27, no. 1 (2019), pp.146-163.
https://search.emarefa.net/detail/BIM-1094632
American Medical Association (AMA)
Abd al-Husayn, Jasim Muhammad& Awdah, Sadun A.& Hasan, Sama Muhammad. Preparation, characterization of a new cis-iodoplatin and Cis-carboplatin complexes and study there spectral, physical and pharmaceutical properties. Journal of Babylon University : Journal of Applied and Pure Sciences. 2019. Vol. 27, no. 1, pp.146-163.
https://search.emarefa.net/detail/BIM-1094632
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 163
Record ID
BIM-1094632
