VEGF +936 CT Genetic Polymorphism in Patients with Cervical Dysplasia
Joint Authors
Popp, Radu A.
Rotar, Ioana Cristina
Dumitras, Diana Elena
Petrisor, Felicia Maria
Cotutiu, Paul
Stamatian, Florin
Muresan, Daniel
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-12
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Aim.
The present study aims to analyze the potential role of VEGF +936 C/T polymorphism in cervical intraepithelial neoplasia.
Material and Method.
One hundred and eighty-six patients were included in the study: 75 cases (patients diagnosed with CIN) and 111 controls (negative for both HPV testing and cytology).
For each patient a single visit was scheduled when colposcopy was performed.
From cervical specimen, cytology and HPV testing were performed and from peripheral blood VEGF +936 genotyping was determined.
For statistical analysis purposes OR and chi-square were used at a level of significance of <0.05.
Results.
No link has been found in the detection of CT genotype in cases versus controls, OR = 0.8295, [0.42, 1.62].
An inverse correlation has been found between T allele and HSIL, OR = 0.2121, [0.0473, 0.9517], p=0.0866.
Conclusion.
No link has been found between VEGF +936 C/T and cervical intraepithelial neoplasia.
American Psychological Association (APA)
Rotar, Ioana Cristina& Dumitras, Diana Elena& Popp, Radu A.& Petrisor, Felicia Maria& Cotutiu, Paul& Stamatian, Florin…[et al.]. 2016. VEGF +936 CT Genetic Polymorphism in Patients with Cervical Dysplasia. Analytical Cellular Pathology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1094967
Modern Language Association (MLA)
Rotar, Ioana Cristina…[et al.]. VEGF +936 CT Genetic Polymorphism in Patients with Cervical Dysplasia. Analytical Cellular Pathology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1094967
American Medical Association (AMA)
Rotar, Ioana Cristina& Dumitras, Diana Elena& Popp, Radu A.& Petrisor, Felicia Maria& Cotutiu, Paul& Stamatian, Florin…[et al.]. VEGF +936 CT Genetic Polymorphism in Patients with Cervical Dysplasia. Analytical Cellular Pathology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1094967
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1094967