Haploidentical Stem Cell Transplantation in Adult Haematological Malignancies
Joint Authors
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-30
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Haematopoietic stem cell transplantation is a well-established treatment option for both hematological malignancies and nonmalignant conditions such as aplastic anemia and haemoglobinopathies.
For those patients lacking a suitable matched sibling or matched unrelated donor, haploidentical donors are an alternative expedient donor pool.
Historically, haploidentical transplantation led to high rates of graft rejection and GVHD.
Strategies to circumvent these issues include T cell depletion and management of complications thereof or T replete transplants with GVHD prophylaxis.
This review is an overview of these strategies and contemporaneous outcomes for hematological malignancies in adult haploidentical stem cell transplant recipients.
American Psychological Association (APA)
Parmesar, Kevon& Raj, Kavita. 2016. Haploidentical Stem Cell Transplantation in Adult Haematological Malignancies. Advances in Hematology،Vol. 2016, no. 2016, pp.1-16.
https://search.emarefa.net/detail/BIM-1095098
Modern Language Association (MLA)
Parmesar, Kevon& Raj, Kavita. Haploidentical Stem Cell Transplantation in Adult Haematological Malignancies. Advances in Hematology No. 2016 (2016), pp.1-16.
https://search.emarefa.net/detail/BIM-1095098
American Medical Association (AMA)
Parmesar, Kevon& Raj, Kavita. Haploidentical Stem Cell Transplantation in Adult Haematological Malignancies. Advances in Hematology. 2016. Vol. 2016, no. 2016, pp.1-16.
https://search.emarefa.net/detail/BIM-1095098
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1095098