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Donor Specific Anti-HLA Antibody and Risk of Graft Failure in Haploidentical Stem Cell Transplantation
Joint Authors
Kongtim, Piyanuch
Cao, Kai
Ciurea, Stefan O.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-24
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Outcomes of allogeneic hematopoietic stem cell transplantation (AHSCT) using HLA-half matched related donors (haploidentical) have recently improved due to better control of alloreactive reactions in both graft-versus-host and host-versus-graft directions.
The recognition of the role of humoral rejection in the development of primary graft failure in this setting has broadened our understanding about causes of engraftment failure in these patients, helped us better select donors for patients in need of AHSCT, and developed rational therapeutic measures for HLA sensitized patients to prevent this unfortunate event, which is usually associated with a very high mortality rate.
With these recent advances the rate of graft failure in haploidentical transplantation has decreased to less than 5%.
American Psychological Association (APA)
Kongtim, Piyanuch& Cao, Kai& Ciurea, Stefan O.. 2016. Donor Specific Anti-HLA Antibody and Risk of Graft Failure in Haploidentical Stem Cell Transplantation. Advances in Hematology،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1095099
Modern Language Association (MLA)
Kongtim, Piyanuch…[et al.]. Donor Specific Anti-HLA Antibody and Risk of Graft Failure in Haploidentical Stem Cell Transplantation. Advances in Hematology No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1095099
American Medical Association (AMA)
Kongtim, Piyanuch& Cao, Kai& Ciurea, Stefan O.. Donor Specific Anti-HLA Antibody and Risk of Graft Failure in Haploidentical Stem Cell Transplantation. Advances in Hematology. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1095099
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1095099