![](/images/graphics-bg.png)
Clinical Scenarios for Discordant Anti-Xa
Joint Authors
Vera-Aguilera, Jesus
Yousef, Hindi
Beltran-Melgarejo, Diego
Teng, Teng Hugh
Jan, Ramos
Mok, Mary
Vera-Aguilera, Carlos
Moreno-Aguilera, Eduardo
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Anti-Xa test measures the activity of heparin against the activity of activated coagulation factor X; significant variability of anti-Xa levels in common clinical scenarios has been observed.
Objective.
To review the most common clinical settings in which anti-Xa results can be bias.
Evidence Review.
Guidelines and current literature search: we used PubMed, Medline, Embase, and MEDION, from 2000 to October 2013.
Results.
Anti-Xa test is widely used; however the assay underestimates heparin concentration in the presence of significant AT deficiency, pregnancy, end stage renal disease, and postthrombolysis and in patients with hyperbilirubinemia; limited published data evaluating the safety and effectiveness of anti-Xa assays for managing UH therapy is available.
Conclusions and Relevance.
To our knowledge this is the first paper that summarizes the most common causes in which this assay can be affected, several “day to day” clinical scenarios can modify the outcomes, and we concur that these rarely recognized scenarios can be affected by negative outcomes in the daily practice.
American Psychological Association (APA)
Vera-Aguilera, Jesus& Yousef, Hindi& Beltran-Melgarejo, Diego& Teng, Teng Hugh& Jan, Ramos& Mok, Mary…[et al.]. 2016. Clinical Scenarios for Discordant Anti-Xa. Advances in Hematology،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1095100
Modern Language Association (MLA)
Vera-Aguilera, Jesus…[et al.]. Clinical Scenarios for Discordant Anti-Xa. Advances in Hematology No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1095100
American Medical Association (AMA)
Vera-Aguilera, Jesus& Yousef, Hindi& Beltran-Melgarejo, Diego& Teng, Teng Hugh& Jan, Ramos& Mok, Mary…[et al.]. Clinical Scenarios for Discordant Anti-Xa. Advances in Hematology. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1095100
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1095100