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Relative Susceptibilities of ABO Blood Groups to Plasmodium falciparum Malaria in Ghana
Joint Authors
Nwaefuna, Ekene K.
Afoakwah, Richmond
Aubyn, Edmond
Prah, James
Boampong, J. N.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-15
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The clinical outcome of falciparum malaria in endemic areas is influenced by erythrocyte polymorphisms including the ABO blood groups.
Studies have reported association of ABO blood group to resistance, susceptibility, and severity of P.
falciparum malaria infection.
Individuals with blood group “A” have been found to be highly susceptible to falciparum malaria whereas blood group “O” is said to confer protection against complicated cases.
We analyzed samples from 293 young children less than six years old with malaria in the Korle-Bu Teaching Hospital in Accra, Ghana.
It was observed that group O was present in about 16.1% of complicated cases weighed against 40.9% of uncomplicated controls.
Individuals with complicated malaria were about twice likely to be of blood groups A and B compared to group O (A versus O, OR = 1.90, 95% CI = 1.59–2.26, P < 0.0001 ; B versus O, OR = 1.82.
95% CI = 1.57–2.23, P < 0.0001 ).
Blood group O participants with complicated diseases had low parasitaemia compared to the other blood groups ( P < 0.0001 ).
This may give blood group O individuals a survival advantage over the other groups in complicated malaria as suggested.
Participants with complicated falciparum malaria were generally anaemic and younger than those with uncomplicated disease.
American Psychological Association (APA)
Afoakwah, Richmond& Aubyn, Edmond& Prah, James& Nwaefuna, Ekene K.& Boampong, J. N.. 2016. Relative Susceptibilities of ABO Blood Groups to Plasmodium falciparum Malaria in Ghana. Advances in Hematology،Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1095102
Modern Language Association (MLA)
Afoakwah, Richmond…[et al.]. Relative Susceptibilities of ABO Blood Groups to Plasmodium falciparum Malaria in Ghana. Advances in Hematology No. 2016 (2016), pp.1-4.
https://search.emarefa.net/detail/BIM-1095102
American Medical Association (AMA)
Afoakwah, Richmond& Aubyn, Edmond& Prah, James& Nwaefuna, Ekene K.& Boampong, J. N.. Relative Susceptibilities of ABO Blood Groups to Plasmodium falciparum Malaria in Ghana. Advances in Hematology. 2016. Vol. 2016, no. 2016, pp.1-4.
https://search.emarefa.net/detail/BIM-1095102
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1095102