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Autologous Graft-versus-Tumor Effect: Reality or Fiction?
Author
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
In contrast to allogeneic hematopoietic stem cell transplantation, the current dogma is not an evidence of graft-versus-tumor effect in autologous hematopoietic stem cell transplantation; thus, it is assumed that autologous hematopoietic stem cell transplantation only relies on the high-dose chemotherapy to improve clinical outcomes.
However, recent studies argue in favor of the existence of an autologous graft-versus-tumor without the detrimental complications of graft-versus-host disease due to the nonspecific immune response from the infused donor alloreactive immune effector cells in allogeneic hematopoietic stem cell transplantation.
Herein, this paper reviews the clinical evidence of an autologous graft-versus-tumor effect based on the autograft collected and infused host immune effector cells and host immunity recovery after autologous hematopoietic stem cell transplantation affecting clinical outcomes in cancer patients.
American Psychological Association (APA)
Porrata, Luis F.. 2016. Autologous Graft-versus-Tumor Effect: Reality or Fiction?. Advances in Hematology،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1095103
Modern Language Association (MLA)
Porrata, Luis F.. Autologous Graft-versus-Tumor Effect: Reality or Fiction?. Advances in Hematology No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1095103
American Medical Association (AMA)
Porrata, Luis F.. Autologous Graft-versus-Tumor Effect: Reality or Fiction?. Advances in Hematology. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1095103
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1095103