Intestinal Parasite Profile in the Stool of HIV Positive Patients in relation to Immune Status and Comparison of Various Diagnostic Techniques with Special Reference to Cryptosporidium at a Tertiary Care Hospital in South India
Joint Authors
Kaniyarakkal, Vishnu
Mundangalam, Nizamuddin
Moorkoth, Anitha Puduvail
Mathew, Sheela
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-07-17
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Acquired immunodeficiency syndrome and related opportunistic infections are a significant cause of morbidity and mortality in susceptible population.
This study aims to negate the paucity of data regarding the relation between CD4 levels, prevalence of enteric parasites, and the outcome of treatment with HAART (highly active antiretroviral therapy) and Cotrimoxazole in Kerala, India.
Multiple stool samples from 200 patients in a cross-sectional study were subjected to microscopy and Cryptosporidium stool antigen ELISA.
Parasites were identified in 18 samples (9%).
Cystoisospora and Cryptosporidium spp.
were seen in 9 cases (4.5%) and 5 cases (2.5%), respectively.
Microsporidium spores and Chilomastix mesnili cysts were identified in 1 case each (0.5% each).
Seven cases of Cystoisospora diarrhoea recovered after treatment with Cotrimoxazole.
Diarrhoea due to Cryptosporidium spp.
in all 5 cases subsided after immune reconstitution with HAART.
This study concludes that a positive association was seen between low CD4 count (<200 cells/μL) and overall parasite positivity ( P value < 0.01).
ELISA is a more sensitive modality for the diagnosis of Cryptosporidium diarrhoea.
Chilomastix mesnili, generally considered a nonpathogen, may be a cause of diarrhoeal disease in AIDS.
Immune reconstitution and Cotrimoxazole prophylaxis remain to be the best therapeutic approach in AIDS-related diarrhoea.
American Psychological Association (APA)
Kaniyarakkal, Vishnu& Mundangalam, Nizamuddin& Moorkoth, Anitha Puduvail& Mathew, Sheela. 2016. Intestinal Parasite Profile in the Stool of HIV Positive Patients in relation to Immune Status and Comparison of Various Diagnostic Techniques with Special Reference to Cryptosporidium at a Tertiary Care Hospital in South India. Advances in Medicine،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1095317
Modern Language Association (MLA)
Kaniyarakkal, Vishnu…[et al.]. Intestinal Parasite Profile in the Stool of HIV Positive Patients in relation to Immune Status and Comparison of Various Diagnostic Techniques with Special Reference to Cryptosporidium at a Tertiary Care Hospital in South India. Advances in Medicine No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1095317
American Medical Association (AMA)
Kaniyarakkal, Vishnu& Mundangalam, Nizamuddin& Moorkoth, Anitha Puduvail& Mathew, Sheela. Intestinal Parasite Profile in the Stool of HIV Positive Patients in relation to Immune Status and Comparison of Various Diagnostic Techniques with Special Reference to Cryptosporidium at a Tertiary Care Hospital in South India. Advances in Medicine. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1095317
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1095317