Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method

Joint Authors

Zhang, Qiang
You, Renchuan
Li, Xiufang
Feng, Yanfei
Yan, Shuqin
Qu, Jing

Source

Advances in Materials Science and Engineering

Issue

Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2016-08-11

Country of Publication

Egypt

No. of Pages

7

Abstract EN

The goal of this study was to fabricate Antheraea pernyi silk fibroin (ASF) microparticles using electrospinning under mild processing conditions.

To improve processability of the ASF solution, poly(ethylene oxide) (PEO) was used to regulate viscosity of ASF solution for electrospinning.

It was found that the blend of ASF with PEO could form a bead-on-string structure with well spherical particles.

Furthermore, aqueous ethanol and ultrasonic treatments could disrupt the nanofibrillar string structure between particles and ultimately produced water-insoluble ASF particles with submicron scale.

Cell viability studies indicated that the ASF microparticles were nontoxic to EA926 cells.

Moreover, fluorescent images based on FITC labeling showed that the ASF microparticles were easily uptaken by the cells.

Aqueous-based electrospinning provides a potentially useful option for the fabrication of ASF microparticles based on this unique fibrous protein.

American Psychological Association (APA)

Li, Xiufang& Zhang, Qiang& Feng, Yanfei& Yan, Shuqin& Qu, Jing& You, Renchuan. 2016. Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method. Advances in Materials Science and Engineering،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1096430

Modern Language Association (MLA)

Li, Xiufang…[et al.]. Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method. Advances in Materials Science and Engineering No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1096430

American Medical Association (AMA)

Li, Xiufang& Zhang, Qiang& Feng, Yanfei& Yan, Shuqin& Qu, Jing& You, Renchuan. Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method. Advances in Materials Science and Engineering. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1096430

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1096430