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Effects of Zoledronate on Mortality and Morbidity after Surgical Treatment of Hip Fractures
Joint Authors
Cengiz, Ömer
Polat, Gökhan
Karademir, Gökhan
Tunç, Oytun Derya
Tuncay, İbrahim
Şen, Cengiz
Erdil, Mehmet
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We aimed to evaluate the effects of intertrochanteric femoral fractures on mortality, morbidity, and cost of zoledronate treatment in elderly patients treated by osteosynthesis.
Based on Evans classification, 114 patients with unstable intertrochanteric femoral fractures were treated with osteosynthesis.
After the surgical treatment of intertrochanteric fractures, the treatment group (M/F, 24/32; mean age, 76.7 ± SD years) received zoledronate infusion, and the control group (M/F, 20/38; mean age, 80.2 ± SD years) received placebo.
Postoperative control visits were performed at 6-week, 3-month, 6-month, and 12-month time points.
Functional level of patients was evaluated by the modified Harris hip score and Merle d’Aubigné hip score.
By 12 months, the mean HHS in treatment and control groups was 81.93 and 72.9, respectively.
For time of death of the patients, mortality was found to be 57.1% (16/28) on the first 3 months and 92.9% (26/28) on the first six months.
The mortality rate in the treatment and control groups was 14.3% (8/56) and 34.5% (20/58), respectively.
The use of zoledronic acid after surgical treatment of intertrochanteric femoral fractures in osteoporotic elderly patients is a safe treatment modality which helps to reduce mortality, improves functional outcomes, and has less side effects with single dose use per year.
American Psychological Association (APA)
Cengiz, Ömer& Polat, Gökhan& Karademir, Gökhan& Tunç, Oytun Derya& Erdil, Mehmet& Tuncay, İbrahim…[et al.]. 2016. Effects of Zoledronate on Mortality and Morbidity after Surgical Treatment of Hip Fractures. Advances in Orthopedics،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1096546
Modern Language Association (MLA)
Cengiz, Ömer…[et al.]. Effects of Zoledronate on Mortality and Morbidity after Surgical Treatment of Hip Fractures. Advances in Orthopedics No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1096546
American Medical Association (AMA)
Cengiz, Ömer& Polat, Gökhan& Karademir, Gökhan& Tunç, Oytun Derya& Erdil, Mehmet& Tuncay, İbrahim…[et al.]. Effects of Zoledronate on Mortality and Morbidity after Surgical Treatment of Hip Fractures. Advances in Orthopedics. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1096546
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096546