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Arguments Reinforcing the Three-Domain View of Diversified Cellular Life
Joint Authors
Da Cunha, Violette
Caetano-Anollés, Gustavo
Kim, Kyung Mo
Nasir, Arshan
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-05
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The archaeal ancestor scenario (AAS) for the origin of eukaryotes implies the emergence of a new kind of organism from the fusion of ancestral archaeal and bacterial cells.
Equipped with this “chimeric” molecular arsenal, the resulting cell would gradually accumulate unique genes and develop the complex molecular machineries and cellular compartments that are hallmarks of modern eukaryotes.
In this regard, proteins related to phagocytosis and cell movement should be present in the archaeal ancestor, thus identifying the recently described candidate archaeal phylum “Lokiarchaeota” as resembling a possible candidate ancestor of eukaryotes.
Despite its appeal, AAS seems incompatible with the genomic, molecular, and biochemical differences that exist between Archaea and Eukarya.
In particular, the distribution of conserved protein domain structures in the proteomes of cellular organisms and viruses appears hard to reconcile with the AAS.
In addition, concerns related to taxon and character sampling, presupposing bacterial outgroups in phylogenies, and nonuniform effects of protein domain structure rearrangement and gain/loss in concatenated alignments of protein sequences cast further doubt on AAS-supporting phylogenies.
Here, we evaluate AAS against the traditional “three-domain” world of cellular organisms and propose that the discovery of Lokiarchaeota could be better reconciled under the latter view, especially in light of several additional biological and technical considerations.
American Psychological Association (APA)
Nasir, Arshan& Kim, Kyung Mo& Da Cunha, Violette& Caetano-Anollés, Gustavo. 2016. Arguments Reinforcing the Three-Domain View of Diversified Cellular Life. Archaea،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1096643
Modern Language Association (MLA)
Nasir, Arshan…[et al.]. Arguments Reinforcing the Three-Domain View of Diversified Cellular Life. Archaea No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1096643
American Medical Association (AMA)
Nasir, Arshan& Kim, Kyung Mo& Da Cunha, Violette& Caetano-Anollés, Gustavo. Arguments Reinforcing the Three-Domain View of Diversified Cellular Life. Archaea. 2016. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1096643
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096643