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Cluster-Randomized Controlled Study of SMS Text Messages for Prevention of Mother-to-Child Transmission of HIV in Rural Kenya
Joint Authors
Kassaye, Seble
Ong’ech, John
Sirengo, Martin
Kose, Judith
Matu, Lucy
McOdida, Peter
Simiyu, Rogers
Syengo, Titus
Muthama, David
Machekano, Rhoderick
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-08
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Antiretroviral medications are key for prevention of mother-to-child transmission (PMTCT) of HIV, and transmission mitigation is affected by service delivery, adherence, and retention.
Methods.
We conducted a cluster-randomized controlled study in 26 facilities in Nyanza, Kenya, to determine the efficacy of SMS text messages on PMTCT outcomes.
The relative risk and confidence intervals were estimated at the facility level using STATA.
Results.
550 women were enrolled, from June 2012 to July 2013.
The median age was 25.6 years, and 85.3% received ARVs.
Maternal ARV use was similar between the intervention and control arms: 254/261 (97.3%) versus 241/242 (99.6%) at 34–36 weeks of gestation and 234/247 (94.7%) versus 229/229 (100%) at delivery.
Among infants, 199/246 (80.9%) and 209/232 (90.1%) received ARVs (RR: 0.91; 95% CI: 0.77–1.14); 88% versus 88.6% were tested for HIV at 6 weeks, with 1/243 (0.4%) and 3/217 (1.4%) positive results in the intervention and control arms, respectively.
Communication increased in both the intervention and control arms, with the mean number of 7.5 (SD: 5.70) compared with 6 (SD: 9.96), p<0.0001.
Conclusions.
We identified high ARV uptake and infant HIV testing, with very low HIV transmission.
Increased communication may influence health-seeking behaviors irrespective of technology.
The long-term effectiveness of facilitated communication on PMTCT outcomes needs to be tested.
The study has been registered on ClinicalTrials.gov under the identifier NCT01645865.
American Psychological Association (APA)
Kassaye, Seble& Ong’ech, John& Sirengo, Martin& Kose, Judith& Matu, Lucy& McOdida, Peter…[et al.]. 2016. Cluster-Randomized Controlled Study of SMS Text Messages for Prevention of Mother-to-Child Transmission of HIV in Rural Kenya. AIDS Research and Treatment،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1096691
Modern Language Association (MLA)
Kassaye, Seble…[et al.]. Cluster-Randomized Controlled Study of SMS Text Messages for Prevention of Mother-to-Child Transmission of HIV in Rural Kenya. AIDS Research and Treatment No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1096691
American Medical Association (AMA)
Kassaye, Seble& Ong’ech, John& Sirengo, Martin& Kose, Judith& Matu, Lucy& McOdida, Peter…[et al.]. Cluster-Randomized Controlled Study of SMS Text Messages for Prevention of Mother-to-Child Transmission of HIV in Rural Kenya. AIDS Research and Treatment. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1096691
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096691