HIV-Associated Oral Mucosal Melanin Hyperpigmentation: A Clinical Study in a South African Population Sample
Joint Authors
Feller, Liviu
Chandran, R.
Lemmer, J.
Khammissa, Razia A. G.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
The aim of the study was to determine the prevalence of HIV-associated oral mucosal melanin hyperpigmentation (HIV-OMH) in a specific population of HIV-seropositive South Africans and to analyse the associations between HIV-OMH clinical features and the demographic and immunological characteristics of the study cohort.
Material and Methods.
This cross-sectional study included 200 HIV-seropositive Black subjects.
The collected data comprised age, gender, CD4+ T cell count, viral load, systemic disease, medications, oral site affected by HIV-OMH, extent (localized or generalized), intensity of the pigmentation (dark or light), and smoking and snuff use.
Results.
Overall, 18.5% of the study cohort had HIV-OMH.
Twenty-two and a half percent had OMH that could not with confidence be attributed to HIV infection, and 59% did not have any OMH.
There was a significant but weak association between smoking and the presence of HIV-OMH.
Conclusions.
The prevalence of HIV-OMH in the study population was 18.5%, the gingiva being the most commonly affected site.
It appears that the CD4+ T cell count does not play any role in the biopathology of HIV-OMH.
American Psychological Association (APA)
Chandran, R.& Feller, Liviu& Lemmer, J.& Khammissa, Razia A. G.. 2016. HIV-Associated Oral Mucosal Melanin Hyperpigmentation: A Clinical Study in a South African Population Sample. AIDS Research and Treatment،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1096712
Modern Language Association (MLA)
Chandran, R.…[et al.]. HIV-Associated Oral Mucosal Melanin Hyperpigmentation: A Clinical Study in a South African Population Sample. AIDS Research and Treatment No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1096712
American Medical Association (AMA)
Chandran, R.& Feller, Liviu& Lemmer, J.& Khammissa, Razia A. G.. HIV-Associated Oral Mucosal Melanin Hyperpigmentation: A Clinical Study in a South African Population Sample. AIDS Research and Treatment. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1096712
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096712