Pharmacological Relaxation of the Ureter When Using Ureteral Access Sheaths during Ureterorenoscopy: A Randomized Feasibility Study in a Porcine Model
Joint Authors
Lildal, Søren Kissow
Andreassen, Kim Hovgaard
Christiansen, Frederikke Eichner
Jung, Helene
Pedersen, Malene Roland
Osther, Palle Jörn Sloth
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-20
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
High intraluminal pressure during ureterorenoscopy (URS) increases risk of infectious and haemorrhagic complications.
Intrarenal pressure may be reduced by the use of ureteral access sheaths (UASs), which on the other hand may cause ureteral damage.
We have previously shown that the β-agonist isoproterenol (ISO), when administered topically in the irrigation fluid, is able to inhibit ureteral muscle tone and lower intrarenal pressure during URS.
The aim of this study was to examine the effect of ISO on the success rate of UAS insertion in a porcine model.
Materials and Methods.
22 pigs in which a UAS could not initially be placed were randomized to endoluminal irrigation with either ISO (0.1 μg/mL) or saline before a new insertion trial.
Subsequently, it was registered whether the UAS could be passed without resistance.
During extraction of the sheath, any ureteral lesions were characterized ureteroscopically using the PULS classification system.
Surgeons were blinded to randomization.
Results.
In the ISO group, the observed effect of irrigation was 63% successful UAS insertions, compared to 27% in the saline group.
No serious lesions ( Conclusions. Endoluminal irrigation with ISO may facilitate UAS insertion and potentially decrease UAS related ureteral lesions.
American Psychological Association (APA)
Lildal, Søren Kissow& Andreassen, Kim Hovgaard& Christiansen, Frederikke Eichner& Jung, Helene& Pedersen, Malene Roland& Osther, Palle Jörn Sloth. 2016. Pharmacological Relaxation of the Ureter When Using Ureteral Access Sheaths during Ureterorenoscopy: A Randomized Feasibility Study in a Porcine Model. Advances in Urology،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1096754
Modern Language Association (MLA)
Lildal, Søren Kissow…[et al.]. Pharmacological Relaxation of the Ureter When Using Ureteral Access Sheaths during Ureterorenoscopy: A Randomized Feasibility Study in a Porcine Model. Advances in Urology No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1096754
American Medical Association (AMA)
Lildal, Søren Kissow& Andreassen, Kim Hovgaard& Christiansen, Frederikke Eichner& Jung, Helene& Pedersen, Malene Roland& Osther, Palle Jörn Sloth. Pharmacological Relaxation of the Ureter When Using Ureteral Access Sheaths during Ureterorenoscopy: A Randomized Feasibility Study in a Porcine Model. Advances in Urology. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1096754
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096754