Vitamin D-Regulated MicroRNAs: Are They Protective Factors against Dengue Virus Infection?
Joint Authors
Arboleda, John F.
Urcuqui-Inchima, Silvio
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-11
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Over the last few years, an increasing body of evidence has highlighted the critical participation of vitamin D in the regulation of proinflammatory responses and protection against many infectious pathogens, including viruses.
The activity of vitamin D is associated with microRNAs, which are fine tuners of immune activation pathways and provide novel mechanisms to avoid the damage that arises from excessive inflammatory responses.
Severe symptoms of an ongoing dengue virus infection and disease are strongly related to highly altered production of proinflammatory mediators, suggesting impairment in homeostatic mechanisms that control the host’s immune response.
Here, we discuss the possible implications of emerging studies anticipating the biological effects of vitamin D and microRNAs during the inflammatory response, and we attempt to extrapolate these findings to dengue virus infection and to their potential use for disease management strategies.
American Psychological Association (APA)
Arboleda, John F.& Urcuqui-Inchima, Silvio. 2016. Vitamin D-Regulated MicroRNAs: Are They Protective Factors against Dengue Virus Infection?. Advances in Virology،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1096769
Modern Language Association (MLA)
Arboleda, John F.& Urcuqui-Inchima, Silvio. Vitamin D-Regulated MicroRNAs: Are They Protective Factors against Dengue Virus Infection?. Advances in Virology No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1096769
American Medical Association (AMA)
Arboleda, John F.& Urcuqui-Inchima, Silvio. Vitamin D-Regulated MicroRNAs: Are They Protective Factors against Dengue Virus Infection?. Advances in Virology. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1096769
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1096769